dimer

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Related to Homodimerization: dimeric, Homodimers, Heterodimerization

dimer

Chem
a. a molecule composed of two identical simpler molecules (monomers)
b. a compound consisting of dimers

dimer

[′dī·mər]
(chemistry)
A molecule that results from a chemical combination of two entities of the same species, for example, the chlorine molecule (Cl2) or cyanogen (NCCN).
References in periodicals archive ?
Matsuo et al., "Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization," Cancer Medicine, vol.
The proosteogenic effect of Wnt5a could be mediated by activation and homodimerization of the receptor Ror2 in hMSCs, whereas Wnt3a has no effect on Ror2 activation and homodimerization [45,-46].
Inhibition of homodimerization of toll-like receptor 4 by 4-oxo-4-(2-oxo-oxazolidin-3-yl)-but-2enoic acid ethyl ester.
As a monomer, PKR is inactive, but its binding with dsRNA or highly structured RNAs induces its homodimerization and stimulates its autophosphorylation and auto-activation (39).
Non-invasive genetic diagnosis of male infertility using spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization. Hum Mol Genet 2006;15: 3411-9.
The amino acid sequence identity shared and the biochemical mechanism by which the DZF domain mediates homodimerization are unique to this group (McCarty et al., 2003).
Constitutive activation of nuclear factor -kB: preferntial homodimerization of p50 subunits in cervical carcinoma.
A novel proximity assay for the detection of proteins and protein complexes: quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffin-embedded cell lines and breast cancer tissue.
HERmark is a proprietary diagnostic that accurately quantifies HER2 total protein expression and HER2 homodimerization in patients with breast cancer.
Four N-terminal zinc-fingers mediate sequence-specific DNA-binding, while two C-terminal zinc-fingers mediate homodimerization and heterodimerization within the family.