homozygote

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homozygote

(hō'mōzī`gōt): see geneticsgenetics,
scientific study of the mechanism of heredity. While Gregor Mendel first presented his findings on the statistical laws governing the transmission of certain traits from generation to generation in 1856, it was not until the discovery and detailed study of the
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The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Homozygote

 

a cell or an organism in whose genetic makeup the homologous chromosomes carry the identical form of a given gene. A homozygote originates during the fusion of gametes that are identical for a given gene. The genetic formula of a diploid organism homozygous for allele A or a can be written in the form AA or aa; for a triploid organism, AAA or aaa; and so forth.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.

homozygote

[¦hō·mə′zī‚gōt]
(genetics)
An individual who has identical alleles at one or more loci and therefore produces identical gametes with respect to these loci.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
However, in one male, CC homozygote was identified in more advanced tumor than in female tumors, and therefore, in the male subgroup, a significant negative correlation with cT (p=0.004) was observed.
Also, different phases of follicles are absent in case of mutant homozygote A allele of G(199)A locus.
Polymorphism Winter SOB IL1B rs16944 CC homozygotes T allele carriers n = 33 n = 42 16.6411.24 18.69 8.95 IL4 rs2243250 (1) CC homozygotes T allele carriers n = 55 n = 20 19.53 9.73 13.00 9.35 IL-1RN VNTR Allele 2 Allele 2 carriers noncarriers n = 28 n = 47 16.7910.48 18.38 9.77 Polymorphism Nonwinter SOB IL1B rs16944 CC homozygotes T allele carriers n = 98 n= 105 17.7611.64 17.6410.77 IL4 rs2243250 (1) CC homozygotes T allele carriers n = 129 n = 74 17.20 11.26 18.54 11.03 IL-1RN VNTR Allele 2 Allele 2 carriers noncarriers n= 111 n = 92 17.74 11.02 17.6411.41 Note.
In terms of INR levels of the patient group, no statistical difference was found between VKORC 1 and CYP2C9 haplotypes (p=0.305 and p=0.088, respectively), whereas a significant difference was found on weekly warfarin dosages of VKORC 1 homozygote normal GG and CYP2C9 *1/*1 homozygote normal (wild) carriers (p=0.02 and p=0.034, respectively) (Table 4).
It would be particularly beneficial for animals with long gestation period to save the time required for breeding for the production of homozygote animals from the verified heterozygotes.
As shown in Figure 7, TCAP 10,10 and 20,20 homozygotes diverge after 50-100 DOF.
Severe iron overload in p.C282Y homozygotes may cause cirrhosis, primary liver cancer, diabetes, other endocrinopathies, and cardiomyopathy [15,16].
L: Ladder 100bp; C+: positive control; C-: negative control; CC: cleavage control; S1: homozygote genotype AA; S2: heterozygote genotype AG; S3: homozygote genotype GG; S4: homozygote genotype AA; S5: heterozygote genotype AC; S6: homozygote genotype CC.
Eight FMO3 wild-type (FMO3 HHDD) subjects and seven FMO3 homozygotes E158K and E308G mutant (FMO3 hhdd) subjects were recruited from 247 healthy male volunteers genotyped by PCR-RFLP method.
Furthermore, as presented above, consanguineous marriages within families that carry familial translocations can result in formation of homozygotes for Robertsonian translocations.