Isaac Schiff of Massachusetts General Hospital, told doctors last month that it was time for a balanced, analytical debate on hormone therapy
This was a secondary analysis of data from the READ study (Radiological Evaluation and Breast Density), a trial designed to test whether short-term suspension of hormone therapy
resulted in better screening mammography performance.
Major Finding: Radiological Evaluation and Breast Density (READ) trial analysis predicts 2 months of disturbed sleep after stopping hormone therapy
The long-term risk-benefit ratio of hormone therapy
is still not known, although answers may emerge from WHI participants who are still being followed, Dr.
Promotion and prescribing of hormone therapy
after report of harm by the Women's Health Initiative.
In prospective studies, greatest risk was observed in current users of hormone therapy
(RR = 1.
Although our findings show that menopausal hormone therapy
may increase the risk of major GI bleeding, especially in the lower GI tract, it is important for these patients to know that this therapy is still an effective treatment; however, both clinician and patient should be more cautious in using this therapy in some cases, such as with patients who have a history of ischemic colitis," Dr.
Pellet hormone therapy
has been widely used in Europe and Australia since 1939.
The primary objective of this Phase 2 study is to assess the combined effects of OGX-011 and neoadjuvant hormone therapy
on pathologic response rates (elimination of all tumor cells) and suppression of clusterin levels in men with high risk localized prostate cancer.
The 10 postmenopausal women in the study, ages 50-60, were given hormone therapy
or a placebo for four weeks, followed by a month with no medications, and then four weeks of the other treatment.
We are confident that the WHI findings, if objectively assessed and incorporated, have given physicians and their patients reasons to reconsider alternative and equally effective methods of postmenopausal hormone therapy
That's when researchers abruptly halted part of the Women's Health Initiative (WHI), a major federally funded clinical study to assess the effect of long-term use of hormone therapy