Howell-Jolly bodies


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Howell-Jolly bodies

[′hau̇·əl ′jäl·ē ‚bäd·ēz]
(pathology)
Small, round basophilic inclusions of nuclear material in erythrocytes of splenectomized persons.
References in periodicals archive ?
(2) These inclusions appear in neutrophils and morphologically and cytochemically resemble Howell-Jolly bodies of normoblasts in abnormal erythropoiesis.
Morphological alterations of RBCs Anisocytosis 19 260 Poikilocytosis 11 37 Target cells 24 11 Microcytes 7 3 Spherocytes 5 2 Polychromic RBCs 3 1 Howell-jolly bodies 4 1 Immature nucleated 24 16 RBCs Rouleaux 29 17 5.
Laboratory testing was significant for white blood cell count of 53.3 G/L, and differential included 88% neutrophils, 4.5% lymphocytes, 3.3 G/L monocytes, 0.15 G/L basophils, 3+ poikilocytosis, 2+ polychromasia, 1+ Howell-Jolly bodies, and 1+ vacuolated polymorphonuclear lymphocytes with target and sickle cells present.
acute renal failure (creatinine, 2.02 mg/dl), lactic acidosis (LA) (lactic acid, 11 mg/dl), and Howell-Jolly bodies on peripheral smear.
Moreover, we did not observe any accumulation of circulating dead parasites (Howell-Jolly bodies), which is against the hypothesis of functional asplenia.