homeobox

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homeobox

[′hō·mē·ə‚bäks]
(cell and molecular biology)
A highly conserved sequence of deoxyribonucleic acid (DNA) that occurs in the coding region of development-controlling regulatory genes and codes for a protein domain that is similar in structure to certain DNA-binding proteins and is thought to be involved in the control of gene expression during morphogenesis and development.
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Nanog and Hox genes each have their own distinct jobs and by inhibiting each other they work together to direct the proper balance of cell states by helping the cell avoid wrong turns and stay on course.
1999), the number of Hox genes increased from eight genes in the protostome ancestor to at least 10 Hox genes in the lophotrochozoan ancestor (Fig.
Russell, "Genomic Approaches to Understanding Hox Gene Function," Advances in Genetics 76 (2011): 55-91.
Determination of the identity of the derivates of the cephalic neural crest: incompatibility between Hox gene expression and lower jaw development.
In previous work (2008 a) this author alluded to the use of macros in Lisp to model the action of Hox genes.
Class1 genes called Hox genes share a high degree of identity in their homeodomain.
In humans, as in other mammals, the embryo's development is controlled, in part, by "architect" genes known as Hox genes.
Background: Molecular events that cause tumor formation upregulate a number of HOX genes, called switch genes, coding for RNA polymerase II transcription factors.
The various Hox genes are situated very close to one another in the chromosome, in groups or clusters.
His research focuses on mechanisms of Hox gene regulation by the mixed-lineage leukemia protein and the role of Hox genes in hematopoiesis and leukemia.
A multitude of fine books have already been written about evo-devo, but they mostly assume that the reader already knows a great deal about developmental and evolutionary biology Forms of Becoming is intended for the nonspecialist who wants an introduction to the field, but be forewarned: it leans toward an academic piece of writing and Minelli assumes that you already know a bit about Hox genes and molecular homologies.
In biology, there is a short DNA sequence called homeobox that appears in eight different genes and the "eight genes that contain homeobox are called Hox genes.