It provides quantitation of erythrocytes and leukocytes, semi-quantitative assessment of bacteria, epithelial cells, and hyaline casts
, and qualitative evaluation of pathologic casts, crystals, yeast, sperm, and mucus.
RBC, WBC, squamous epithelial cells, hyaline casts
, and bacteria are enumerated.
Urinalysis showed large blood and hyaline casts
. Toxicology and heavy metal screenings were unremarkable.
The presence of pathologic casts or other particles was not confirmed in one-half of the cases because high numbers of hyaline casts
, ECs, and cell debris also can cause such flags.
Patients with chronic nephrotoxicity have focal acute tubular necrosis characterized by cystic dilated tubules lined by a flattened epithelium showing atypical nuclei and atypical mitotic figures with hyaline casts
. Long-term cisplatin treatment and injury may cause cyst formation and interstitial fibrosis.
The analyzer classifies images into categories including RBC, WBC, WBC clumps, hyaline casts
, unclassified casts, EC, nonsquamous EC, bacteria, yeast, crystals, mucus, sperm, and amorphous substances.
Quantitative counts were obtained for bacteria (BACT channel, counting particles with diameter [greater than or equal to] 2 [micro]m), RBCs, white blood cells (WBCs), casts (CAST channel; gated to detect mainly inclusion-bearing granular or cellular casts because hyaline casts
are difficult to discern from slime threads with such an analyzer), large epithelial cells (ECs), and small round cells (SRCs; including both epithelial and inflammatory cells).
Urinalysis showed proteinuria (>500mg/dl), moderate hemoglobinuria, hyaline casts
(41/LPF), WBC (28/HPF), and RBC (81/HPf).