human papillomavirus

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Related to Hybrid capture: Hybrid Capture assay

human papillomavirus

(HPV), any of a family of more than 60 viruses that cause various growths, including plantar wartswart,
circumscribed outgrowth of the skin caused by a filterable virus that is readily transmitted. Warts may appear anywhere on the skin but are most common on the hands.
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 and genital warts, a sexually transmitted diseasesexually transmitted disease
(STD) or venereal disease,
term for infections acquired mainly through sexual contact. Five diseases were traditionally known as venereal diseases: gonorrhea, syphilis, and the less common granuloma inguinale, lymphogranuloma venereum, and
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. Detectable warts can be or removed, usually by chemicals, freezing, or laser, but often recur. Intralesional alpha interferon has been effective in the treatment of genital warts. Genital warts, sometimes called condylomata acuminata, are soft and often occur in clusters. They can occur internally or externally, but even in the absence of warts the virus may be present and transmittable. Problems can result from untreated warts, which can grow quite large, or, in rare cases, from infection of an infant during delivery. In addition, certain strains of HPV are associated with cancercancer,
in medicine, common term for neoplasms, or tumors, that are malignant. Like benign tumors, malignant tumors do not respond to body mechanisms that limit cell growth.
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 of the cervix, vulva, vagina, penis, and anus, and HPV 16 has been shown to be associated with some forms of Kaposi's sarcoma (see AIDSAIDS
or acquired immunodeficiency syndrome,
fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. It was first recognized as a disease in 1981.
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) and throat cancer. A vaccine approved by the Food and Drug Administration in 2006 can protect a woman against those strains that cause most cases of cervical cancer and genital warts, and a study has shown it may also protect against related throat cancers; HPV vaccination is now recommended for both girls and boys beginning at 11 to 12 years of age.

human papillomavirus

[¦yü·mən ‚pap·ə′lō·mə ‚vī·rəs]
(medicine)
One of a family of more than 100 different viruses, most commonly spread via sexual contact, that cause warts on the hands and feet and in the genital area; several types are associated with premalignant and malignant changes in the cervix. Abbreviated HPV.
References in periodicals archive ?
Sensitivity of high-risk HPV Hybrid Capture II (hrHPV HC2) test using SurePath[TM] specimens in the prediction of cervical high-grade squamous lesions.
HPV DNA detection by various methods such as fluorescent in situ hybridization, PCR, and hybrid capture assays has further revolutionized the detection of HPV infections quite early before the lesions are visible clinically.
Moreover, the sensitivity of the hybrid capture test for CT is lower than the test based on nucleic acid amplification.
Presence of human papillomavirus infection determined by hybrid capture assayin cervical lesions in a Venezuelan population.
INDEX TERMS: Molecular Methods, Polymerase Chain Reaction, Real-Time PCR, TaqMan Probes, Molecular Beacons, Dual Hybridization Probes, Fluorescence Resonance Energy Transfer; Transcription-Medicated Amplification, Hybridization Protection Assay, Hybrid Capture, FDA Cleared Molecular Viral Assays.
Presently, the two assays most widely used for the detection of genital types are PCR with generic primers and the Hybrid Capture 2 assay (Digene Corp, Gaithersburg, MD, USA).
Use of a hybrid capture assay of self-collected swabs in rural Uganda for detection of human papilloma virus.
In a separate vote, ACIP also recommended vaccination for women with an equivocal or abnormal Pap test, those who have tested positive for HPV infection using the Hybrid Capture II, and for those with genital warts.
The samples were tested using a Hybrid Capture II assay to test for high-risk HPV types 16, 18, 31, and 33.
and tested for HPV with the Hybrid Capture 2 assay (Digene Corp.