Also found in: Dictionary, Medical, Wikipedia.
Related to Hydroxylamine: Semicarbazide


(inorganic chemistry)
NH2OH A colorless, crystalline compound produced commercially by acid hydrolysis of nitroparaffins, decomposes on heating, melts at 33°C; used in organic synthesis and as a reducing agent.



H2NOH, is the product of the replacement of one hydrogen atom in the ammonia molecule (NH3) by an OH group. It forms colorless acicular crystals. Density, 1,204.4 kg/m3 (at 23.5° C); melting point, 33°-34° C; boiling point, 58° C at 2.933 kilonewtons per sq m (22 mm Hg). Hydroxylamine is stable at 0° C; at 20° C it decomposes slowly. An increase in temperature accelerates the decomposition, and at 130° C it explodes.

Hydroxylamine is hygroscopic. It dissolves readily in water to form hydroxylamine hydrate, which is a weak base: NH2OH·H2O ⇆ NH3OH+ + OH. Upon reaction with acids, hydroxylamine hydrate gives hydroxyammonium salts—for example, NH3OHCl and (NH3OH)2SO4—which have strong reducing properties. Hydroxylamine dissolves readily in methyl and ethyl alcohols but is insoluble in acetone, benzene, and petroleum ether. It is oxidized by atmospheric oxygen to HNO2. Hydroxylamine sulfate is produced industrially by reducing sodium nitrite with sulfur dioxide in the presence of sodium carbonate. Free hydroxylamine is produced by distilling alkaline solutions of the salts. Hydroxylamine and its derivatives are poisonous. Salts of hydroxylamine are extensively used in the pharmaceutical industry, in making kapron, and in analytical chemistry.


Brikum, I. K., M. T. Kozlovskii, and L. V. Nikitina. Gidrazin igidroksilamin i ikh primenenie v analiticheskoi khimii. Alma-Ata, 1967.


References in periodicals archive ?
To 200 [micro]l sample in ethanol, 100 [micro]l hydroxylamine solution was added and incubated at room temperature for 30 minutes.
Hydroxylamines and hydroxylamine salts as combustion improvers for liquid biomass-derived and hydrocarbon-based fuels.
Brave Dream, trained by Jim Old, showed promise in a couple of bumpers last season, particularly at Ascot on his debut, and he can win Taunton's Hydroxylamine National Hunt Flat Race (4.
The researchers speculate that hydroxylamine, which can cause mutations in human as well as bacterial DNA, could contribute to the eventual development of gastric cancer.
Moreover, disproportionation to olefin + hydroxylamine requires on the order of hours to reach measurable conversion, indicating that alkoxyamine stability is sufficient for the purposes of polyolefin crosslinking.
Ammonia, a non-ionic surfactant, a proteinase and hydroxylamine neutral sulphate (HNS) are added into the field latex and allowed to react for 72 hours in a reaction tank.
85), followed by extraction of the reducible metal fraction by hydroxylamine hydrochloride (0.
Oxime ether pyrethroids and hydroxylamine ether propyrethroids: photochemistry, biological activity, and metabolism.
N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro.
3) of nitrate reducing bacteria in rumen, and then to ammonia via hydroxylamine.