Hyperkeratosis

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Related to Hyperkeratinization: keratosis pilaris

hyperkeratosis

[¦hī·pər·ker·ə′tō·səs]
(medicine)
Hypertrophy of the cornea.
Hypertrophy of the horny layer of the skin.

Hyperkeratosis

 

excessive development of the corneous layer of the skin in humans. Hyperkeratosis may be caused by external factors (such as prolonged pressure, friction, or the effects of lubricating oils) or internal factors (endocrine dysfunctions, hypovitaminosis A, occupational intoxication). Hyperkeratosis is manifested by the formation of horny plates, nodes of various sizes, protuberances, and spurs; the skin becomes dry and perspiration decreases. Hyperkeratosis may be accompanied by the formation of painful cracks (on the palms and soles). It may be limited (calluses, warts, keratomas) or diffuse, spread over large areas or the entire skin surface (ichthyosis). Treatment consists in soda or soap baths, vitamin therapy, and medications that dissolve the horny substance.

References in periodicals archive ?
Acne is a multifactorial disease involving a combination of hyperkeratinization in the sebaceous follicles, excess sebum production, and overgrowth of the bacteria Propionibacterium acnes.
With the use of an unprcceden ted test method on normal human sebocytes as a more reliable and predictive model associated with cosmetogenomics, Sederma was able to confirm a positive action on every known process leading to oily skin and associated blemishes: hyperseborrhea, microbial proliferation, inflammation, hyperkeratinization and hyperpigmentation.
An unprecedented test using normal human sebocytes as a more reliable predictive model associated to a cosmetogenomic approach confirms an action for each step of the process leading to oily skin and associated blemishes: hypersebonhoea, microbial proliferation, inflammation, hyperkeratinization and hyperpigmentation.
Addresses all five key acne targets: Hyperkeratinization, Bacterial population, Sebum control, Inflammation and Pigmentation.