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Condition caused by increased functioning of the parathyroid glands.



a disease caused by excessive production of the hormone of the parathyroid glands, usually occurring as the result of adenoma of those glands.

An excess of parathyroid hormone mobilizes the calcium in the bones, raises its level in the blood and lowers the level of phosphorus, and raises the quantity of calcium and phosphorus in the urine (which is then discharged). Softening and deformation of the bones is the result of this process, making possible spontaneous fracture or fracture caused by minimal injury. Visceropathic forms of hyperparathyroidism are characterized by calcium deposits in the internal organs. The most widespread is the renal form (formation of calculi in the kidneys and urinary tracts). The cause of formation of adenomas in the parathyroid glands is not known. Hyperparathyroidism is more commonly found in women. Treatment involves removal of the tumor; orthopedic treatment is necessary when the disease affects the bones, and removal of the calculi is necessary in nephrolithiasis.


References in periodicals archive ?
8,9 GCMB gene expression is observed to be up-regulated in presence of hyperparathyroidism, and down-regulated in presence of hypocalcaemia.
It is important to have a high index of suspicion to diagnose primary hyperparathyroidism and avoid delaying management of the patients.
Spontaneous resolution of primary hyperparathyroidism in parathyroid adenoma.
The report reviews key players involved Secondary Hyperparathyroidism therapeutics and enlists all their major and minor projects
1 Specific clinical symptoms of primary hyperparathyroidism include pathological changes of the digestive, nervous, skeletal and urinary systems and skin, which may be misdiagnosed as rheumatic and rheumatoid arthritis.
A most unusual finding was the complete resolution of pulmonary calcification after 18 months of medical treatment for secondary hyperparathyroidism.
SCD may be associated with endocrine disorders like hyperparathyroidism which also cause generalized body pains.
Husain, "The association of primary hyperparathyroidism with pancreatitis," Journal of Clinical Gastroenterology, vol.
The association between renal impairment, low 25(OH)-vitamin D, anemia, marrow fibrosis, severe osteoporosis, fibrocystic osteitis, high level of alkaline phosphatase and considerable volume of the parathyroid adenoma suggested a long neglected primary hyperparathyroidism and were considerable risk factors for a postoperative hungry bone syndrome.
A review of the Secondary Hyperparathyroidism products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
The company said Doxercalciferol Injection is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis.
The study involved 100 people with primary hyperparathyroidism (PHPT) from the New York area who were enrolled between December 2010 and February 2014.