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Extremely high fever.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



elevation of the body temperature in humans and animals caused by a disturbance in heat loss. A fever of 42°C is considered critical: lethal changes in the brain tissue develop. The critical temperature for an individual may range from 40° to 44°C. A few cases have been recorded in which persons with a temperature of 44°C have recovered. Moderate hyperpyrexia may be induced artificially for therapeutic purposes (treatment of syphilis and other diseases). Artificially induced hyperpyrexia is called hyperthermia.


Fizicheskie faktory vneshnei sredy [v usloviiakh proizvodstva]. Edited by A. A. Letavet. Moscow, 1960.
Mnogotomnoe rukovodstvo po patologicheskoi fiziologii, vol. 2. Moscow [1966].
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The medical history reported by the patient was heat intolerance and suffering from hyperpyrexia, frequent colds, and otitis, and recurrent respiratory tract infections were described.
The excess activity induced by sympathetic overdrive and hyperpyrexia induced by serotonin leads to rhabdomyolysis which can potentially lead to myoglobinuria and renal failure [1].
Bromocriptine is a synthetic dopamine agonist; however, the mechanism by which resolution of symptoms including hyperpyrexia and dysautonomia are achieved is unclear (Russo & O'Flaherty, 2000).
CIPA commonly presents with orthopedic problems and hyperpyrexia. Its sign and symptoms usually appear at birth or early infancy, because of the inability to feel pain which is the main feature of this condition usually resulting in unintentional self-trauma.
Factors that increase the likelihood of bacteraemia in febrile children include toxicity, hyperpyrexia and malnutrition.
The warning signs are hyperpyrexia ( fever above 102 Celsius), severe bodyache, eye pain ( pain behind the eyeballs), petechiae ( rash), severe vomiting, diarrhoea, dehydration and altered consciousness.
Death and life-threatening effects: It results in Tosade de pointes, serotonin syndrome, ventricular arrhythmia, or hyperpyrexia.
Fatty acid oxidation in the mitochondria is the major energy source particularly for endothelial cells and heart muscle, (55),(56) under several conditions of metabolic stresses, such as long fasting, prolonged exercise, infection and hyperpyrexia. (57),(58) The carnitine palmitoyltransferase (CPT) system is the rate-limiting step in the importation of long-chain fatty acids into the mitochondria and CPT II deficiency is one of the common inborn errors of fatty acid oxidation.
Despite intensive therapy about 50% of acute clinical cases with hyperpyrexia and respiratory distress and septicemic symptoms could be saved.
Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status, and evidence of autonomic Instability (Irregular pulse or blood pressure, tachycardia, diaphoresis, and cardiac dysrhythmia).
Deaths associated with Ecstasy have been reported, often as a result of hyperpyrexia brought on by high levels of exertion, high ambient temperatures, and inadequate fluid intake.
The prodromal stage of paralytic rabies shows hyperpyrexia, headache, emesis, and pain at the site of the wound.