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Related to Hypertensive nephropathy: Hypertensive nephrosclerosis


Sclerosis of the renal arteries and arterioles.



a condition of kidneys arising during the final stage of hypertensive disease and accompanied by a proliferation of connective tissue and the onset of uremia. Nephrosclerosis arises less frequently in such diseases as atherosclerosis of the principal vessels of the kidneys, pyelonephritis, tuberculosis of the kidneys, diffuse glomerulonephritis, and nephrolithiasis.

When occurring in conjunction with hypertension, nephrosclerosis is accompanied by hyalinosis and necrosis of the small arteries of the kidneys. In pronounced cases of nephrosclerosis, the kidneys become smaller and acquire a granular surface. Occasionally, the surface appears nodular. In cases of malignant hypertension, early diagnosis of nephrosclerosis is possible only through a biopsy of the kidney; tests of kidney function and X-ray and radioisotopic tracer analyses are also carried out.

Treatment involves a salt-free diet, agents that decrease arterial pressure, and antibacterial measures in cases complicated by infection. Surgical treatment is recommended in some instances of renal injury.


Miasnikov, A. L. Gipertonicheskaia bolezn’i ateroskleroz. Moscow, 1965.
Osnovy nefrologii, vol. 2. Edited by E. M. Tareev. Moscow, 1972.
Pochki. Edited by F. K. Mostofi and D. E. Smith. Moscow, 1972. (Translated from English.)


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Proteinuria, particularly microalbuminuria, is a known early marker of hypertensive nephropathy in adults.
This was predominantly attributable to a higher prevalence of recipients with hypertensive nephropathy, diabetes, BMI [greater than or equal to] 30 kg/[m.
The underlying etiology of end stage renal disease were diabetic nephropathy 69(46%), hypertensive nephropathy 51(34%), obstructive nephropathy 18 (12%), glomerulonephritis 9(6%), autosomal polycystic kidney disease 3(2%)(Table-1).
Diabetic nephropathy (a) 28 Hypertensive nephropathy 11 Focal segmental glomerulosclerosis (b) 7 Collapsing glomerulopathy (c) 2 Granulomatous tubulointerstitial nephritis (d) 2 Acute pyelonephritis 1 Thrombotic microangiopathy 1 Atheroembolic disease 1 Reflux nephropathy (e) 1 Proliferative glomerulonephritis (f) 1 Membranous glomerulonephritis (g) 1 Amyloidosis 1 (a) All patients had clinical diabetes.
Hypertensive nephropathy is a medical condition referring to damage to the kidney due to chronic high blood pressure.

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