Hypertrichosis


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Hypertrichosis

 

the excessive growth of hair on a person’s body where only downy hairs usually grow.

There are several kinds of hypertrichosis. Heterogeneous hypertrichosis occurs in girls and women; it is the appearance of a beard, moustache, or male-type hair growth. (In men, pubic hair grows in a diamond shape; in women, in the form of a triangle with the upper boundary the horizontal side.) Hair growth increases during the period of sexual development and before or during the climacteric. Heterochronous hypertrichosis is the premature appearance of hair as a secondary sex characteristic (the appearance of a beard, moustache, or pubic hair in children). It is caused by a developmental anomaly or a disease of the endocrine glands. Heterotypic hypertrichosis is an increased amount of hair in unusual places, such as the small of the back. Hypertrichosis can be partial, local, or distributed over the whole body. Limited hypertrichosis can be either hereditary or elicited by prolonged mechanical, chemical, thermal, or physical trauma.

In women with excessive growth of downy hairs on the face or extremities, pulling out the hairs, shaving, or applying greasy creams or depilatories can cause significant thickening of the hairs, which become coarse and stiff and begin to grow faster than usual. An application of a 10-15 percent solution of hydrogen peroxide makes the hairs colorless and less noticeable but does not curtail their growth. Depilatories (preparations which dissolve the core of the hair and do not affect the papillae from which they grow) can be applied in extreme cases and only on covered parts of the body. The best treatment consists of electroepilation with the aid of electrolysis, ultrahigh frequency, and diathermy.

M. A. ROZENTUL

References in periodicals archive ?
At six months of age, a low weight and height were documented as well as generalized hypertrichosis. The occurrence of this neurological symptoms together with persistent hypertrichosis at 12 months led to an assessment by a pediatric endocrinologist, who ruled out an androgenic hormone disorder (normal testosterone levels, [alpha]-OH-progesterone and somatomedin).
Typical symptoms of RMS include growth retardation, elfin face, gingival hyperplasia, acanthosis nigricans, hypertrichosis and insulin resistance.
Pseudoacromegalic findings include elfin faces; large and low-set ears; wide nostrils; thick lips; gingival hypertrophy; large mouth, hands and feet; hypertrichosis; dysplastic nails; and acanthosis nigricans (2, 3-5).
Major criteria Polyneuropathy Monoclonal plasmaproliferative disorder Minor criteria Sclerotic bone lesion Castleman's disease Organomegaly Edema (edema, pleural effusion, and ascites) Endocrinopathy (adrenal, thyroid, pituitary, gonadal, parathyroid, and diabetes ([double dagger])) Skin changes (hyperpigmentation, hypertrichosis, plethora, hemangioma, and white nails) Papilledema Other signs Clubbing, weight loss, hyperhidrosis, pulmonary hypertension, thrombotic diatheses, diarrhea, and low vitamin B12 * Two major criteria and at least 1 minor criterion are required for diagnosis [11].
Clinical examination at 5 years of age noted some dysmorphic features such as microcephaly, round face, hypertrichosis, low anterior hairline, sparse hair with abundant hair fall, hypotelorism, synophrys, small and low-set ears, concave nasal ridge, thick lips, widely spaced teeth, and micrognathia.
There was no comedo-like lesions, cafe au lait macules, or hypertrichosis on the surface of the lesion.
Caption: Figure 1: He had a moon face appearance with truncal obesity, buffalo hump, hypertrichosis in trunk, and purple striae in the axilla, periumbilical, and inguinal region.
It is characterized by pattern of severe mental retardation, dysmorphic features, hypertrichosis, and multiple congenital anomalies, including skeletal abnormalities, cardiac, genitourinary, and renal malformations [1, 2].
Katritzky focuses on the hypertrichosis, excessive hair growth, which affected Pedro Gonzales, 'The Wild Man of Tenerife'.
Although sharing some similar syndromes, TBS and ZLS patients show distinct features: the former is characterized by intellectual disability, epilepsy, and hypoplasia or aplasia of the nails of the thumb and great toes [101, 102], and the latter is characterized by gingival enlargement, intellectual disability, hypoplasia or absence of all nails and terminal phalanges, and hypertrichosis and associated with or without epilepsy [103105], respectively.
In 1987, Koifman and colleagues published a case-control study with 175 users of Norplant[R] in Rio de Janeiro, showing "a statistically significant increase in the risks among Norplant users of menstrual disorders, hypertension, serious weight disturbances and hypertrichosis," and suggested "the removal of Norplant from all Brazilian women, under the supervision of public institutions from the health sector" (30).
(9-10) A newly coined term 'prostaglandin-associated periorbitopathy' (PAP) (see Figure 1) has been proposed as the general term to describe the periocular changes associated with topical PGA therapy and includes DUES, upper eyelid ptosis/retraction, loss of inferior orbital fat pads and enophthalmos, eyelid pigmentation and eyelash hypertrichosis. (11-12)