Hypoparathyroidism


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Related to Hypoparathyroidism: hyperparathyroidism, pseudohypoparathyroidism

hypoparathyroidism

[‚hī·pō‚par·ə′thī‚rȯi‚diz·əm]
(medicine)
Condition caused by insufficient functioning of the parathyroid gland.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Hypoparathyroidism

 

a condition caused by insufficient secretory activity of the parathyroid glands.

Hypoparathyroidism may arise after the removal of the parathyroid glands or after their injury during thyroid surgery. Hypoparathyroidism is accompanied by disorders in calcium metabolism, a disturbance in the assimilability of calcium in the gastrointestinal tract, lowered calcium content in the blood, and deformation of the teeth. The disturbance in calcium metabolism increases the excitability of the nervous system, and an inclination to spasms (tetany) appears. Spasms arise spontaneously or under the influence of provocative factors (for example, muscle strain, overheating, and contusions) in symmetrical groups of muscles (most often of the upper extremities, more rarely of the lower extremities, and even more rarely in the facial and other muscles). Hypoparathyroidism occurs in both latent and manifest forms. The latent form may not be outwardly evident and is manifested only in a fall in temperature of the extremities, paresthesia throughout the body, and spasms. Pregnancy, menstruation, mechanical and thermal irritation, poisoning, and infections can stimulate the transition from latent to manifest hypoparathyroidism. Treatment involves hormonal and vitamin therapy.

L. M. GOL’BER

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Results from Part 1 of this study, reported in 2018, demonstrated a positive impact of Oral PTH on three metabolic parameters - serum calcium, phosphate, and 1,25-dihydroxyvitamin D ('active' vitamin D) - in patients with hypoparathyroidism. There was also a decrease in 24-hour urine calcium in the patients treated with Oral PTH.
In the present study we tried to find out factors which can predict the occurrence of post-operative hypocalcaemia & hypoparathyroidism in total thyroidectomy patients, facilitating their early detection and institution of definitive management in time, preventing emergency admissions & catastrophes.
[9] succeeded to treat the treatment-resistant hypoparathyroidism through PTH in short-interval pulse-type to mimic physiological PTH release.
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Total thyroidectomy is associated with increased prevalence of permanent hypoparathyroidism. Med Sci Monit 2014; 20:1675-81.
Entera is conducting clinical trials for two candidate drugs treating three indications: hypoparathyroidism, osteoporosis, and non-union fractures.
"The inability of petitioner GMA to leave for abroad to alleviate, or, at least, prevent the aggravation of her hypoparathyroidism and metabolic bone disorder has given rise to the danger that the said conditions afflicting petitioner GMA may become permanent and incurable," Mrs.
Arroyo was supposed to seek medical treatment in Singapore, Spain and possibly in Germany for her hypoparathyroidism and metabolic bone disorder.