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Condition caused by insufficient secretion of pituitary hormones, especially of the adenohypophysis. Also known as panhypopituitarism.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a chronic condition caused by reduced internal secretion of the pituitary body.

Hypopituitarism is manifested by insufficiency of function of the thyroid, adrenal cortex, and gonads. Trauma, tumors, infections, and hemorrhages in the area of the base of the brain can result in hypopituitarism. Hypopituitarism is manifested in arrested growth (nanism), impairment of lipometabolism, causing obesity or severe emaciation (cachexia), or underdevelopment of the sexual organs. In women with hypopituitarism, menstruation ceases and the uterus, ovaries, and mammary glands atrophy. In men the testicles and penis atrophy. Physical and mental languor, frequent dizziness, buzzing in the ears, headaches, sleepiness, susceptibility to fatigue, and a lowering of the basal metabolism are characteristic of hypopituitarism. Pituitary tumors are treated by X-ray and radiotherapy or surgical operation; other forms are treated by hormonal therapy.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The term hypopituitarism denotes the deficiency of one or more of the hormones of the anterior or posterior pituitary gland whereas, panhypopituitarism is defined as the loss of all the pituitary hormones and the term is often used in clinical practice to describe patients with deficiency in growth hormone (GH), gonadotropins, corticotropin, and thyrotropin.
This is in contrast with other studies that reported tumors as the leading cause of pan hypopituitarism. A small study from India reported a frequency of 84% pituitary tumors in patients with panhypopituitarism.11 Another study, from United Kingdom, also reported non-functioning pituitary tumor and craniopharyngioma, as the leading cause for hypopituitarism.12 The reason to seek medical care was symptoms related to mass effect, rather than hormonal dysfunction per se, in patients with Craniopharyngioma in our study.
The surgical option should be avoided in children with prolactinoma because of recurrence after surgery and also because of development of various complications, including hypopituitarism, and the need to restart dopamine agonistic therapy.
Hypopituitarism is the most commonly experienced side effect, which may present in a delayed fashion, and can be predicted by cavernous sinus extension in pre-SRS imaging.
What are the symptoms of hypopituitarism? https://pituitarysociety.org/patient-education/pituitary-disorders/hypopituitarism/how-is-hypopituitarism-treated.
All of them had hypopituitarism, but diabetes insipidus was absent in one patient (4).
A 76-year-old female was diagnosed with underlying Sjogren's syndrome and hypopituitarism after presenting with syncope, reguiring an emergency pacemaker for life-threatening first-degree heart block (8).
Dr Nahar Al Baroodi, Specialist Endocrinologist, Mediclinic Dubai Mall, says, "Hair loss may accompany several endocrine disorders, including hypopituitarism, hypothyreosis, hypoparathyroidism, diabetes mellitus, growth hormone deficiency and polycystic ovary syndrome.
(4) Other initial presentations include anterior hypopituitarism, visual disturbances, fatigue, and headache.
Each chapter addresses an endocrine syndrome and its aspects relating to the metabolic syndrome: hypopituitarism, acromegaly, hyperprolactinemia, thyroid disease, parathyroid diseases, Cushing's syndrome, adrenal insufficiency, polycystic ovary syndrome, male hypogonadism, and central hypogonadotrophic hypogonadism.