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Failure of a tissue or organ to achieve complete development.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



or hypogenesis, underdevelopment of a tissue, organ, part of the body, or entire organism. Just as with aplasia, the basis of hypoplasia is impairment of the interuterine development of the fetus as a result of the effect of radiant energy on the mother’s organism, imbalance in nutrition, and certain infections transmitted from the mother to the fetus, such as German measles, toxoplasmosis, or poliomyelitis.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Congenital Heart Diseases Product Types In-Depth: Hypoplasia, Obstructive & Septal Defects
Biallelic inactivation of the LHCGR causes Leydig cell hypoplasia (LCH, OMIM#238320) that leads to male disorders of sexual differentiation (DSD).
Although rare but when dealing with triad of recurrent pneumonia, right lung hypoplasia and mediastinal shift, physicians should consider possibility of Scimitar syndrome.
Finger and phalangeal abnormalities (clinodactyly, bipartite phalanges and phalangeal hypoplasia) were noticed in four cases.
Adrenal hypoplasia congenita is a rare disorder that can be inherited as an X-linked or autosomal recessive pattern.
The largest difference was observed in patients with albinism (-0.76 logMAR) and the least difference was observed in those with OD hypoplasia (-0.14 logMAR).
The comparative percentage for occurrence of enamel hypoplasia in giraffids of these Siwalik deposits is early Miocene-early middle Miocene (29%), middle Miocene (20%), late Miocene-early Pliocene (15%), early Pliocene-late Pliocene (26%) and late Pliocene-early Pleistocene (10%).
Moreover, patients were asked about recurrent aphthous stomatitis and examined to detect temporomandibular disorders according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications and defects of the enamel surface of the teeth (e.g., enamel wear disorder and/or enamel hypoplasia) [23].
Funduscopic examination revealed bilateral foveal hypoplasia and optic nerve hypoplasia.
Turner's hypoplasia is a type of hypoplasia characterized by imperfections in a permanent tooth caused by trauma or periapical infections of deciduous teeth and commonly irritate patients aesthetically.
However, the term foveal hypoplasia has also been used to describe cases with expected acuity of 0.44 logMAR, absent extrusion of plexiform layers, absence of foveal pit, presence of outer segment lengthening, and presence of ONL widening [7].
A 5-year-old boy was consulted at the age of 7 months for hypoplasia of his right thumb and active movement disorder.