interferon-gamma

(redirected from IFN gamma)

interferon-gamma

[‚in·tər¦fir‚än ′gam·ə]
(immunology)
An interferon produced by T lymphocytes and large granular lymphocytes in response to foreign macromolecules.
References in periodicals archive ?
ALT (IU/ml) 69,18 20,6 0,003 IFN gamma (pg/ml) 4,41 5,52 0,015 TC (mmol/L) 2,55 3,61 <0,0001 LDL-C (mmol/L) 1,4 2,03 0,003 HDL-C (mmol/L) 0,8 1,09 0,002 TG (mmol/L) 0,77 1,1 0,16 (ns) r.e.
GAS, IFN gamma activated sequence; H3, histone H3; ISRE, IFN sensitive response element; NPC, nuclear pore complex.
Schreiber, "The roles of IFN gamma in protection against tumor development and cancer immunoediting," Cytokine & Growth Factor Reviews, vol.
Highly sensitive determination of plasma cytokines by time-resolved fluoroimmunoassay; Effect of bicycle exercise on plasma level of interleukin-1 alpha (IL-1 alpha), tumor necrosis factor alpha (TNF alpha), and interferon gamma (IFN gamma).
La concentracion de IFN-[gamma] y IL-4 fue determinada en sobrenadantes de cultivo celular por la tecnica de ELISA, para los cuales se utilizaron los kits comerciales Bovine IFN Gamma ELISA Reagent Set (Genway Biotech[R]) y Bovine Interleukin-4 ELISA Kit (Bio-Rad[R]).
"Now, we succeeded in producing IFN gamma protein from their milk.
"We have identified a new pathway, centered on IFN gamma, that controls the bone remodelling process both in-vivo and in-vitro.
We realised that this differentiation process involved IFN gamma-related genes, but also that these bone cells precursors could both be stimulated by IFN gamma and produced IFN gamma."
In the next step, the researchers focussed on an animal model where IFN gamma effect is blocked by inactivating its receptor-a model called IFN gamma receptor knock-out.
Moreaux et al., "Lymphocytes of dogs immunised with purified excreted-secreted antigens of Leishmania infantum co-incubated with Leishmania infected macrophages produce IFN gamma resulting in nitric oxide-mediated amastigote apoptosis," Veterinary Immunology and Immunopathology, vol.
It will allow researchers to produce the IFN gamma protein more abundantly and cheaply.