References in periodicals archive ?
McKenzie, "Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL13 is a profibrotic agent," The Journal of Immunology, vol.
Inflammation-related upstream regulators like the NF[kappa]B complex are inhibited and IL13 activated.
Compared to MPCs, LPCs exhibited significantly (p < 0.05) higher levels of Th2 pathway cytokines (IL4, IL5, IL10, and IL13), with IL10 showing a 40% increase, and significantly (p < 0.05) lower levels of Th1/Th17 cytokines (IL6, IL12, IL17A, IFN-[gamma], G-CSF, and TGF-[beta]1).
Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1.
However, researchers have discovered that in mice damaged epithelium of mucosa containing innate immune cells secrete Th2 cytokines IL13 and IL5 in response to IL33 and IL25.
These genes encoded cytokines (CSF3, CSF2, CCL3, TNF, CCR1, IL13, KIT, CCL5, CCL4, IL10, CXCL10, IL12RB2, IFNG, IL1B, IL1A, IL8, MET, CD40, HGF, LEP, CXCL16, CX3CR1, CCR2, PDGFRA, IL12B, IL2), lipid metabolism related genes (CD36, GPX4, LPIN1, LPL, LPB), transcription regulators (BCL3, FOS and NFKBIA), receptors (TNF, IL8, RELA, TLR1, TIRAP, TLR2, NFKBIA, NFKB1, TLR4, CD40, CCL5, CXCL10, FOS, JUN, MAP3K8, IL1B, LBP, IL12B, CD14, SPP1), and others such as SELP, SELL, and SOD1, all play a role in some aspect of the immune response including cytokine activity (IL10, TNF, IL8, and IL1B), cell adhesion (SELL and SELP), immune activation (CD14 and TLR2), acute phase reaction (TNF, IL1B, and SAA3), apoptosis (BCL2, BAX).
LPS (100 ng/mL; Sigma-Aldrich, US) or IL-4 and IL13 (20 ng/mL each, R&D, US) were then added for another 24 h incubation.
Xu et al., "Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma," American Journal of Human Genetics, vol.
A recent study examining gene expression of the dorsolateral prefrontal cortex from patients with mood disorders demonstrate an elevated expression of inflammatory agents (IL-1[alpha], IL-2, IL-3, IL-5, IL-8, IL-9, IL-10, IL-12A, IL13, IL-15, IL-18, IFN-[gamma], and lymphotoxin-a) compared to control subjects .
IL8 behaves as a granulocyte recruiting factor ; IFN-gamma disturbs Ag presentation ; IL13 may cause severe colitis .
(48) The abnormal T-cell populations in L-HES produce T helper 2 cytokines, including IL4, IL5, and IL13, and stimulate production of CCL17/TARC (thymus and activation-regulated cytokine); however, testing for production of these cytokines is currently performed using research assays and is not readily available as a clinically validated test.
In non-castrated mice, GM-CSF, eotaxin, lL1b, IL13, and MIP-1b were more expressed in [OMEGA]3-fed mouse tumors.
Encyclopedia browser ?
- Ikhsanova, Liabiba
- Ikhsanova, Liabiba Faizovna
- Ikon Basilike
- Ikonnikov, Vladimir
- Ikonnikov, Vladimir Stepanovich
- Ikonomov, Matei Spasov
- Ikrami, Dzhalol
- Ikramov, Akmal
- Ikramov, Akmal Ikramovich
- Ikramov, Iskandar
- Ikramov, Iskandar Ikramovich
- Ikrianistova, Mariia
- Ikrianistova, Mariia Fedorovna
- Il Domenichino
- Il Parmigianino
- Il Penseroso
- IL Perugino
- Il Popolo
- Il Ruzzante
- ilang-ilang oil
- Ilarion Ilarionovich Shafranovskii
- Ilarion Kalinovich Rossokhin
- Ilarion Rossokhin
- Ilarion Ruvarac
- Ilarion Shafranovskii
- Ilchenko, Aleksandr
- Ilchenko, Aleksandr Eliseevich
- Ildebrando Pizzetti
- Île de France
- Île de la Cité
- Île Jésus
Full browser ?
- Il-Do Tae-Kwon-Do Association
- Il-sung Kim
- Il-sung Kim
- IL12, subunit p40
- IL1RA, CD121 antigen-like family member A