The institution registry was used to identify patients who underwent IORT
from 10/2011 to 2/2017.
When used for IORT
, the Xoft System delivers a single, prescribed, targeted dose of isotope- free radiation eliminating the need for a shielded treatment environment.
delivers a single, more powerful dose of radiation than that used in standard radiation treatments; this helps preserve a larger area of healthy breast tissue and reduces side effects, which may include fatigue, irritated skin at the site of the treatment, and reduced levels of red or white blood cells.
In another report, Rate et al published the outcomes of 47 patients with recurrent head and neck cancer who underwent resection and IORT
.  The 2-year actuarial local control rate was 62%, and the 2-year survival was 55%.
And, although radiation alone has not greatly lengthened long-term survival, patients treated with combined surgery and IORT
do show improved survival--often a year or more longer than patients not receiving radiation.
also involves radiating only the surrounding tissue, not the entire breast, after the tumor is removed.
allows radiation oncologists and breast cancer surgeons to work together to deliver a full dose of radiation at the time of lumpectomy for eligible patients.
Emerging evidence demonstrates the noninferiority of this method and IORT
may become more widely adopted with commensurate impact on the outcomes of BCT.
According to the company, the FDA-approved IORT
's Xoft Axxent system delivers a single, prescribed, targeted dose of radiation during surgery directly to the tumour cavity.
The ExBRT ("A Safety and Efficacy Study of Intra-Operative Radiation Therapy Using the Xoft Axxent Electronic Brachytherapy System at the Time of Breast Conservation Surgery for Early-Stage Breast Cancer") study evaluates traditional external beam radiation therapy versus IORT
using the Xoft System for early-stage breast cancer.
The possibility of delivering intraoperative radiotherapy (IORT
) with electrons, without dedicated equipment, is very attractive.
and / Monetary amount deposited in the bank account of the Municipality of Plovdiv Investbank AD - Plovdiv Branch, IBAN BG 57 IORT
73753302000003, BIC IORTBGSF, or