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Med an abnormal reaction of an individual to specific foods, drugs, or other agents



a painful reaction that appears in certain persons to irritants that do not produce similar phenomena in the majority of others. The basis of idiosyncrasy is either a congenital increased sensitivity of the autonomic nervous system to particular irritants or a reaction that arises in the body as a result of the repeated weak action of certain substances that are incapable of stimulating antibody production in the body.

Idiosyncrasy differs from allergy in that it may develop even after the first contact with an intolerable irritant—for instance, simple chemical compounds that do not have the properties of allergens; such food products as fish, roe, crab, milk, eggs, and strawberries; such medications as amidopyrine, antibiotics, and sulfanilamide preparations; the pollens of certain flowers and plants; the odor of various animals; insect poisons; and such physical factors as sunstroke, chill, or trauma.

Soon after contact with the irritant, headache appears in the individual, and his temperature rises, sometimes accompanied by mental agitation, disruption of the function of the organs of digestion (nausea, vomiting, diarrhea) and respiration (dyspnea, coryza), edema of the skin and mucosa, and urticaria. These phenomena, which are caused by disruptions of blood circulation, increased permeability of the vessels, and spasms of the smooth musculature, usually pass quickly, but sometimes may continue for several days. The reaction does not produce insen-sitivity to the repeated action of the agent. Treatment requires avoidance of further contact with the intolerable irritant and lowering the body’s heightened reactivity.



A peculiarity of constitution that makes an individual react differently from most persons to drugs, diet, treatment, or other situations.
Any special or peculiar characteristic or temperament by which a person differs from other persons.
References in periodicals archive ?
Which explains why the club have decided to pay a two match visit to Northern Ireland next week, where old and new players will have an excellent chance to bond and get to know each other's idiosyncracies.
This is a joyful look at the idiosyncracies of the ordinary person.
That was not the case with Contrabajissimo (1987), Sappington's hallmark solo for Holder that assimilates many of his onstage idiosyncracies into a tour de force of theatrical dancing.
Bookcase says: ''Gloriously depicting not just the momentous occasion of the signing of the all-important document but brilliantly describing all the idiosyncracies of everyday life in an era largely ignored by modern historians.
I now put Churchill, with all his idiosyncracies, his indulgences, his occasional childishness, but also his genius right or wrong, successful or unsuccessful, to be larger than life, as the greatest human being ever to occupy Downing Street.
The lower quotes are based on a cloudy forecast and Headingley's idiosyncracies which have traditionally seen the wickets there favour seam bowlers.
His idiosyncracies come to mind more readily than his improved form, but over 1m6f and 2m (which he has never tried) he is a smart performer in the making.
The true Open won't begin until Sunday afternoon when the converging pressures of winning the Open and dealing with Ross' golf architectural idiosyncracies will clash here at Pinehurst.
Yet there is nothing to be read on its ownership, or the key staff members, or their comments on the idiosyncracies and foibles of the stallions; there are no pictures of the stud locations, or those state-of-the-art breeding barns in their rural setting.
He destroyed champion Ray Barneveld on Saturday, then emerged from a two-day bender - one of his little idiosyncracies - to beat Matt Clark in a match he rarely looked
I've spoken to Brian Harding and he's told me about Addington Boy's idiosyncracies, and I'm looking forward to it.