immunoglobulin E

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immunoglobulin E

[‚im·yə·nō‚gläb·yə·lən ′ē]
(immunology)
A class of immunoglobulins present in minute amounts in normal human serum that is active against parasites and acts as a mediator of immediate hypersensitivity. Abbreviated IgE. Also known as reagin.
References in periodicals archive ?
Dr Grimshaw said the research would highlight to GPs that further tests should be carried out even if an IgE test is negative.
The IGE among adults whose parents were between the 50th and 90th income percentiles is 0.
Researchers stated that total IgE levels for all of the allergens tested were not associated to glaucoma, which suggested that it is specifically the cat and cockroach allergens which are associated with developing glaucoma.
He also touched upon some emerging issues, including the possible risks posed by placing a porcine heart valve or bioprosthetic ligament in a patient with serum IgE antibodies to alpha-gal.
In suspected IgE-mediated allergy, SPT and/or measurement of serum specific IgE antibodies (ImmunoCAP) to suspected foods are used to prove sensitisation.
While the excellent agreement among the 6 clinically used total serum IgE assays has not been questioned in recent years, the data in the current study support this conclusion.
IGE also owns one of Northern Europe's most potent nickel sulphide projects in Northern Sweden, where 340 million tons of nickel ore has been identified (257.
Novomatic made, as always, a significant investment in IGE and we can judge that investment to have been worthwhile.
Anti-DNP IgE was applied to the dorsal skin of rats as follows: anti-DNP IgE (200ng/ml; Sigma-Aldrich Tokyo, Japan) was incubated at the indicated concentrations of [gamma]-oryzanol or cycloartenyl ferulate for 60min, and injected into the dorsal skin of rats by intradermal injection under anesthesia.
To our knowledge this is the first example of such a panel of IgE and IgG4 allergen-specific antibodies.
2 First-time contact with the cat allergen causes special cells, called mast cells, to produce the IgE antibody.
Knowledge of the mechanisms of allergic inflammation has allowed the development of specific pharmacologic intervention to include 1) antibodies to IgE, 2) therapy tailored to regulate IgE production, and 3) modulation of cytokine release and function.