interleukin-6

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Related to Il-6: IL-1b, IL-8

interleukin-6

[‚in·tər¦lük·ən ′siks]
(immunology)
A cytokine derived from activated T lymphocytes that has many functions, including induction of B-cell growth; induction of B-cell differentiation and antibody production; induction of differentiation and proliferation of T cells; synergistic induction with IL-3 of hematopoietic cell growth; and induction of hepatocyte secretion of acute-phase inflammatory proteins. Abbreviated IL-6.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
o IL-1?, IL-1?, IL-2, IL-3, IL-4, IL-5, IL-6, IL-10, IL-12p70, IL-17, MCP-1, IFN-?, TNF?, MIP-1?, GMCSF, RANTES
Table 3 summarizes the mean serum IL-6 level among normal, overweight, and obese categories.
IL-6 and IL-8 ELISA kits were purchased from Neobioscience Technology Co, Ltd., Beijing, China.
Kim, "IL-32gamma induces the maturation of dendritic cells with Th1- and Th17-polarizing ability through enhanced IL-12 and IL-6 production," Journal of Immunology, vol.
Interleukin-6 (IL-6) is a multi-functional cytokine that participates in both physiological and pathological processes6.
Genotyping of samples were obtained for IL-6 C-174G (rs 1800795) SNP by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method and was confirmed on DNA sequencing.
Each sample of DNA was analyzed for polymorphisms in the IL-6 gene at position -174, and in the IL-10 gene at position -597 with PCR-RFLP.
The IL-6 protein synthesis in the coculture supernatants was detected by ELISA.
Conclusion: It was concluded that warfarin alters the inflammatory function of cells by directly influencing the IL-6 and COX-2 levels
It involves accumulation of plaque (comprising of colonies of bacteria, which stick on the tooth surface as a film).1,2 IL-6 being an acute phase reactant is also considered a proinflammatory cytokine, which is involved in the pathogenesis of coronary heart disease through autocrine, paracrine, and endocrine mechanisms.3
We found that IL-6 and IL-6R existed in cells around the inflammatory tissues of RA patients inferring that IL-6 was correlated with ARD joints and played an essential role in its pathogenesis the effect of which is evident in allergic reaction-related parts (Fig.
Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans.