Sangamo Biosciences used a technique which disrupts a gene factor found in immune cells
called CCR5 that is being used by HIV to attach itself, infect and replicate on T-cells.
The research by the Johns Hopkins Children's Center and the Johns Hopkins Institute of Genetic Medicine has found that aberrant signalling by a protein called transforming growth factor-beta, or TGF-beta, may be responsible for disrupting the way immune cells
respond to common foods and environmental allergens, leading to a wide range of allergic disorders.
Washington, Apr 4 (ANI): US researchers have discovered a new way to predict breast cancer survival based on an 'immune profile' - the relative levels of three types of immune cells
within a tumor.
Further, the company will comprehensively support clinical trials of immune cell
therapy conducted at the 22nd Century Medical Center.
It is important because MS is apparently caused by misdirected immune cells
that enter the brain and damage myelin-an insulating material on the branches of neurons that conduct nerve impulses, said researchers.
Liu said that one of the key steps involved in turning on the immune response is the prolonged accumulation of calcium inside of immune cells
In samples of breast cancer patients' lymph nodes, Lee and his colleagues identified unique patterns of immune cells
For instance, in Kirschner's simulation of tuberculosis infection, immune cells
are the agents, and the grid represents a 2-millimeter-square patch of lung tissue, big enough to hold a nascent granuloma.
This group of molecules, produced by immune cells
, turns up or tunes down immune system activity.
The researchers then tracked changes in immune cell
type and found that eotaxin inhibits monocytes becoming dendritic cells (that find foreign invaders so other immune cells
can neutralize them), resulting in more "fighter" cells being present during an allergic response.
Bone marrow transplantation can cure lymphomas and leukemia, but in about half of the cases transplanted immune cells
wind up attacking the patient's body, as well as the cancer.
Nasdaq:MAXM)(SSE:MAXM) announced that clinical researchers presented this weekend results from a Phase 2 study in advanced metastatic melanoma patients demonstrating that combination therapy with Ceplene(TM) (histamine dihydrochloride) and interleukin-2 (IL-2) induced significant and measurable increases in the number and function of key activated immune cells
that are known to target cancer cells.