Immunochemistry


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Immunochemistry

A discipline concerned both with the structure of antibody (immunoglobulin) molecules and with their ability to bind an apparently limitless number of diverse chemical structures (antigens); with the structure, organization, and rearrangement of the genes coding for the immunoglobulin molecules; and with the structure and function of molecules on the surface of animal cells, such as the transplantation (histocompatibility) antigens, which recognize antibodies and the thymus-derived lymphocytes mediating the cellular immune response. See Antigen, Immunoassay, Immunoglobulin, Radioimmunoassay, Transplantation biology

McGraw-Hill Concise Encyclopedia of Bioscience. © 2002 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Immunochemistry

 

a branch of immunology that studies the chemical foundations of immunity. The principal problems of immunochemistry are the study of the structure and properties of immune proteins—antibodies—and natural and synthetic antigens, as well as the elucidation of the laws governing the interactions between these principal components of immunological reactions in various organisms. Immunochemical methods also find practical application, especially during the separation and purification of the active principles of vaccines and serums.

REFERENCES

Boyd, W. C. Vvedenie v immunokhimicheskuiu spetsifichnost’. Moscow, 1963. (Translated from English.)
Immunokhimicheskii analiz. Edited by L. A. Zil’ber. Moscow, 1968.
Kabat, E., and M. Mayer. Eksperimental’naia immunokhimiia. Moscow, 1968. (Translated from English).
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.

immunochemistry

[¦im·yə·nō′kem·ə·strē]
(immunology)
A branch of science dealing with the chemical changes associated with immunity factors.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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We therefore determined the sample dead volumes for chemistry and immunochemistry assays with the different pediatric tubes and the sample cup by requesting replicates of either the chemistry or the immunochemistry assay with the smallest sample volume (glucose and carcinoembryonic antigen; 2 and 10 [micro] L, respectively).
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Citing a need for economical analytical methods for detecting trace levels of hazardous compounds in complex environmental and biological media, Van Emon (director for the immunochemistry program at the US Environmental Protection Agency, National Exposure Research Laboratory) notes that immunochemical methods are capable of achieving very low detection levels and are particularly adaptable.
The company cited data by market researchers according to which the IVD market in the country is estimated to be about USD 400 million (EUR 296.2m), with 70% of such market being composed of immunochemistry (32%), haematology/coagulation (14%) and chemistry/urine analysis (25%).
This reagent is fully automated when run on any of the UniCel DxC Synchron Systems or the IMMAGE immunochemistry system.
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The immunochemistry segment generated the largest portion of IVD revenues in the country, amounting to USD 408.8 million, which contributed 46.6% to the total market in fiscal 2013.