immunotoxin

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immunotoxin

[‚im·yə·nō′täk·sən]
(immunology)
Conjugate of antibody and toxic protein such that the specificity of the antibody molecule is combined with the cytotoxic property of the toxin.
References in periodicals archive ?
Haley et al (50) reported immunotoxic effects in mice following 13-wk exposures to various nickel compounds.
So far, studies in mice suggest that dioxin's immunotoxic punch occurs in extremely low doses and may well be more important than cancer in determining dioxin's primary health risk, adds Birnbaum.
1987), as well as immunotoxic effects at lower internal doses in females (Nielsen and Hultman 2002).
A multiparametric approach for monitoring immunotoxic responses in mussels from contaminated sites in western Mediterranean.
In vitro and in vivo studies have demonstrated adverse effects-- including immunotoxic, neurologic, respiratory, and dermal responses--after exposure to specific toxins, bacteria, molds, or their products.
Preclinical screening and analysis of the immunotoxic and immunomodulatory acitivity using a multiple immunoassay (MIA) in mice.
This interpretation, however, seems unlikely because arsenic is known to be immunotoxic, clinical reports have noted VZV reactivation after arsenic exposure, an estimated 99.
It seems that sumithrin is less immunotoxic to lobsters than resmethrin, which at similar concentrations, significantly reduced phagocytosis on single and repeated exposures in similar experimental conditions (De Guise et al.
This is a revelation of possible immunotoxic effects of BG since the spleen plays a major role in immunological mechanisms.
In vitro characterization of the immunotoxic potential of several perfluorinated compounds (PFCs).
The failure to free the body of toxicants that also invade the immune organs and cause direct immunotoxic suppressive effects leads automatically to ultimate failures in combating numerous infectious agents in these children--candidiasis, parasitosis, Lyme, Strep A, and others--regardless of the conventional or alternative means chosen.
Laboratory studies demonstrated that the pesticides malathion, resmethrin and methoprene are immunotoxic in lobsters, and that sublethal pesticide-related changes to the immune systems of lobsters can occur at certain exposure levels (De Guise et al.