excipient

(redirected from Inactive ingredient)
Also found in: Dictionary, Medical.

excipient

[ek′sip·ē·ənt]
(pharmacology)
Any inert substance combined with an active drug for preparing an agreeable or convenient dosage form.
Mentioned in ?
References in periodicals archive ?
The label of food and pharmaceutical product should also give information regarding inactive ingredients that sometimes becomes objectionable and questionable and abide by the halal food quality standards during the entire process of manufacturing and production of goods meant for human consumption.
1-8] The Physicians' Desk Reference,[9] which is widely used as a source of drug information, does not always list sorbitol as an active or inactive ingredient when present, and when sorbitol is fisted, the concentration is not always specified.
Scientific sessions, workshops and short courses will address topics including: stem cell derived cell lines, Inactive ingredient database and novel excipients, drug product manufacturing, global CMC challenges for break-through designated products, continuous manufacturing, peptide and biologic topics, and more.
If multiple labels were available within a database, we investigated all potential inactive ingredient formulation changes by reviewing the older labels.
Different generic formations may have different inert ingredients, which may cause problems if patients are allergic to a specific inactive ingredient.
In this drug product example, the Ti02 must be considered to be an inactive ingredient in compliance with 21 CFR 330.
Food and Drug Administration (FDA) Inactive Ingredient Search for Approved Drug Products website to determine the maximum concentration already employed in an approved drug product (4).
While drug manufacturers have been investigating a number of available technologies to make replication of their drug products more difficult, one approach being considered involves the addition of trace amounts of an inactive ingredient or ingredients to an existing section (a discrete contained solid or a layer in a solid oral dosage form) of the dosage form.
Pharmaburst is the only ODT excipient system included in the FDA's Inactive Ingredient Guide (IIG), the company contends.
However, many silicones also have been used in healthcare applications, as evidenced by the number of silicone materials listed on the FDA's inactive ingredient list.
The FDA Center for Drug Evaluation and Research's (CDER) 3D printing facility enables FDA scientists to conduct research to determine how the 3D printing of drugs impacts inactive ingredients and other drug components as well as the quality control process of manufacturing.

Full browser ?