Inclusion Bodies


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Inclusion Bodies

 

in biology, all the structures of the cell cytoplasm. Inclusion bodies are usually divided into three groups: fixed bodies, or organoids, which carry out the general cell functions—for example, mitochondria, Golgi bodies, chloroplasts; temporary bodies, or paraplasmatic formations, which appear and disappear during metabolism—secretor granules, nutritive substances, fat, starch, and others; and specialized, or metaplasmatic, formations, which are found in some specialized cells, where they perform particular functions, such as contraction—the myo-fibrils of muscle cells—or support—the tonofibrils in epidermal cells.

References in periodicals archive ?
Refolding and purification of recombinant L-asparaginase from inclusion bodies of E.
SDS-PAGE analysis of recombinant BMP-2 expression confirmed a high level of protein, aggregated as inclusion bodies and entirely not present in soluble fraction, in spite of decreasing IPTG induction temperature below 25 [degrees]C.
The IIF assay showed granular fluorescence areas that displayed the morphology of the inclusion bodies in cell cytoplasms (Figure 2, panel C).
(b) Ampullary biopsy (x100) showing submucosal Brunner's glands showing nucleomegaly with eosinophilic intranuclear and basophilic cytoplasmic inclusion bodies (pointed black arrow) of CMV.
Expression, purification and renaturation of truncated human integrin b1 from inclusion bodies of Escherichia coli.
EGD revealed classic duodenal and esophageal ulcerations and immunohistochemical stains of the biopsy specimens revealed viral inclusion bodies consistent with CMV.
The most pathognomonic feature of this entity is the perinuclear inclusion bodies, which usually are small, round, pale pink bodies on hematoxylin-eosin-stained slides that can indent the nucleus and appear similar to red blood cells (Figure 4).
A 1.5-2 ml virus suspension containing 108 polyhedral inclusion bodies (PIB/ml) was centrifuged at 3000 rpm for 10 min, and the obtained precipitate was fixed with 2.5% glutaraldehyde for 2 h.
Morphological changes in the muscle cells, such as the presence of inclusion bodies, fragmentation, and central core lesions, were quantified by a single observer who examined three random HE-stained fields of equal magnification.
[1] It is characterised by collections of histiocytes containing laminated, calcified Michaelis-Gutmann inclusion bodies. Malakoplakia frequently involves the urinary tract, gastrointestinal tract being the second most common site.
Diagnosis of Ehrlichiosis can be made by identification of inclusion bodies or morula of Ehrlichia canis in leukocytes from blood smears or from buffy coat smears and lymphnode aspiration (Faria 2010).
Histopathological studied revealed intra nuclear inclusion bodies basophilic (INIB) in hepatocytes (Alemnesh et al., 2012).