Inclusion Bodies


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Inclusion Bodies

 

in biology, all the structures of the cell cytoplasm. Inclusion bodies are usually divided into three groups: fixed bodies, or organoids, which carry out the general cell functions—for example, mitochondria, Golgi bodies, chloroplasts; temporary bodies, or paraplasmatic formations, which appear and disappear during metabolism—secretor granules, nutritive substances, fat, starch, and others; and specialized, or metaplasmatic, formations, which are found in some specialized cells, where they perform particular functions, such as contraction—the myo-fibrils of muscle cells—or support—the tonofibrils in epidermal cells.

References in periodicals archive ?
Although no evidence of hepatocytic degeneration or necrosis was seen in the H&E-stained sections of liver from the other 4 animals in this group (MPX-5 to MPX-8), the immunostain for viral antigen highlighted rare inclusion bodies in the hepatocytes of animals MPX-6 and MPX-7, which indicated a small amount of monkeypox virus replication in the liver.
In the liver, most of the larger inclusion bodies stained strongly positive for viral antigen (Figure 1C); however, some of the smaller inclusion bodies were negative.
Inclusion bodies similar to adenoviral inclusion bodies can be induced by other viruses, including polyomavirus, herpesvirus, and circovirus.
Mass purification of nucleopolyhedrosis virus inclusion bodies in the K-Series centrifuge.
Histopathologic evaluation of the skin nodules revealed marked hyperplasia of the epidermis with ballooning degeneration of cells and numerous eosinophilic intracytoplasmic inclusion bodies (Fig 3).
p62 is also found in inclusion bodies containing polyubiquitinated protein aggregates which are present in several neurodegenerative diseases such as Parkinson, Alzheimer, and Huntington's diseases.
Histopathological examination showed splenic parenchyma with discrete, round to oval noncaseating granuloma composed of epithelioid histiocytosis, multinucleated giant cells (Figure 2a), and asteroid inclusion bodies (Figure2b).
System design information sharing at national and international levels, and inclusion bodies responsible for the fight against cyber threats, cyber-terrorism and cyber-crime in this system on the basis of existing or newly defined competencies (National Cyber ?
However, the rapid and high-yield protein production often leads to polypeptide misfolding and results in protein aggregation into inclusion bodies, rendering the target protein biologically inactive.
Langerhans cells have cytoplasmic inclusion bodies known as Birbeck granules; a definitive diagnosis requires electron microscopy of Birbeck granules or CD 1 antigenic determinants by immunohistochemistry.
Cell culture, cytological tests for the detection of cytoplasmic inclusion bodies, direct immunofluorescence (DFA), enzyme-linked immunosorbent assay (ELISA), DNA hybridization techniques and polymerase chain reaction (PCR) are several laboratory methods which are used for the diagnosis of C.
Histology showed multinucleate squamous cells with ground-glass viral nuclear inclusion bodies, indicative of HSV infection.