Indole


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indole

[′in‚dōl]
Also known as 2,3-benzopyrrole.
(biochemistry)
C6H4-(CHNH)CH A decomposition product of tryptophan formed in the intestine during putrefaction and by certain cultures of bacteria.
(organic chemistry)
Carcinogenic, white to yellowish scales with unpleasant aroma; soluble in alcohol, ether, hot water, and fixed oils; melt at 52°C; used as a chemical reagent and in perfumery and medicine.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Indole

 

(2, 3-benzopyrrole), colorless crystals with an unpleasant odor. Melting point, 52°C; boiling point, 254°C. It is soluble in hot water and organic solvents. Indole is present in coal tar, from which it is extracted as salts of alkali metals, as well as in certain essential oils (for example, oil of jasmine). Along with skatole (3-methyl-indole), it is found in the intestines of human beings and mammals.

Many indole derivatives, for example, 3-indoleacetic acid (heteroauxin A, a growth substance), serotonin, and reserpine, are biologically active. Indole is a raw material for synthesizing heteroauxin and tryptophane, and is used in the perfumery industry to improve and strengthen the scents of flower essences.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
We identified at least 1 SCRA in 49 of 160 patients (31%) with the commonest examples being the indole carboxamides 5F-ADB (20), MDMB-CHMICA (8), and 5F-AKB-48 (7).
The first step is the activation of the 3-position carbonyl group of isatin (2) by 60 wt% PWA/MCM-41, which facilitates nucleophilic addition of indole (1) to form corresponding 3-hydroxy-3-indolyl oxindole (5).
Perdew, "Indole and tryptophan metabolism: endogenous and dietary routes to Ah receptor activation," Drug Metabolism and Disposition, vol.
Catalase positive, Indole positive, Oxidase positive
Therefore, the aim of this current study is to evaluate effect of the detoxification herbal formula on transport of indole alkaloids in Caco-2 cells monolayer.
Indole is a typical tryptophan metabolite in the natural environment, acting as plant hormone precursor and microbial signal molecule [5-7].
Another disadvantage of this process is high concentration of indole inhibits TSase activity.
V, Photobiotransformation of indole to its value-added derivatives by Rhodobacter sphaeroides OU5.
Following a sample analysis by the state lab, it emerged that the powder was not cyanuric acid but naphthoyl indole, a chemical powder with effects similar to that of cannabis.
Significant values of correlation coefficient were found between phenol, indole, iso-butyric acid and iso-valeric acid with Atopostipes, p-cresol and skatole with Bacteroides, acetic acid and butyric acid with AM982595_g of Porphyromonadaceae family, and propionic acid with Tissierella.