Also found in: Dictionary, Medical, Legal, Wikipedia.
Related to Indole: skatole, Isoquinoline, Indole test, Indole-3-carbinol


Also known as 2,3-benzopyrrole.
C6H4-(CHNH)CH A decomposition product of tryptophan formed in the intestine during putrefaction and by certain cultures of bacteria.
(organic chemistry)
Carcinogenic, white to yellowish scales with unpleasant aroma; soluble in alcohol, ether, hot water, and fixed oils; melt at 52°C; used as a chemical reagent and in perfumery and medicine.



(2, 3-benzopyrrole), colorless crystals with an unpleasant odor. Melting point, 52°C; boiling point, 254°C. It is soluble in hot water and organic solvents. Indole is present in coal tar, from which it is extracted as salts of alkali metals, as well as in certain essential oils (for example, oil of jasmine). Along with skatole (3-methyl-indole), it is found in the intestines of human beings and mammals.

Many indole derivatives, for example, 3-indoleacetic acid (heteroauxin A, a growth substance), serotonin, and reserpine, are biologically active. Indole is a raw material for synthesizing heteroauxin and tryptophane, and is used in the perfumery industry to improve and strengthen the scents of flower essences.

References in periodicals archive ?
Monoterpene indole alkaloids consist in a terpenoid component derived from the iridoid glucoside secologanin and an indole moiety provided by triptamine (Facchini 2001).
Chemical analysis of AE identified 10-methoxygeis-soschizol, ramiflorine A and ramiflorine B, corynanthe monoterpernoid indole alkaloids, as its major constituents (Ferreira et al.
Preparative separation of indole alkaloids from the rind of Picralima nitida (Stapf) T.
In order to generate the plant material required to produce the monoterpenoid indole alkaloids, several concentrations of cytokinin were tested to select the optimal concentration for induction and multiplication of shoots.
1] Sarangapani M, Jessy Jacob, Srinivas B and Raghunandan N, "Synthesis and CNS Activity of New Indole Derivatives", Indian Drugs 38(5) May 2001(264-268).
Rey se decanta por el termino "burlesco", que se aproximaria mas a la voluntad de Quevedo y que, sobre todo, se encuentra a caballo entre lo meramente ludico o "festivo" y lo "satirico", de indole mas bien moralista.
Cabbage contains indole-3-carbinole (I3C), sulforaphane and indoles, which are thought to help the body's antioxidant mechanisms.
A Gram stain of these colonies identified gramvariable, pleomorphic coccobacilli that were negative for catalase, oxidase, urease, and citrate, and did not produce indole or reduce nitrate.
In the Kyn pathway, the indole ring of Trp can be opened by the enzymes tryptophan pyrrolase [tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase (IDO)] (3).
Indole 3-carbinol is a nutrient from broccoli, cabbage, and other cruciferous vegetables that has been found to reduce breast cancer in numerous studies.
Another product that is rather widely distributed is Green Light Root Stimulator and Starter Solution, which contains indole butyric acid, also an auxin.