Indole

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indole

[′in‚dōl]
Also known as 2,3-benzopyrrole.
(biochemistry)
C6H4-(CHNH)CH A decomposition product of tryptophan formed in the intestine during putrefaction and by certain cultures of bacteria.
(organic chemistry)
Carcinogenic, white to yellowish scales with unpleasant aroma; soluble in alcohol, ether, hot water, and fixed oils; melt at 52°C; used as a chemical reagent and in perfumery and medicine.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Indole

 

(2, 3-benzopyrrole), colorless crystals with an unpleasant odor. Melting point, 52°C; boiling point, 254°C. It is soluble in hot water and organic solvents. Indole is present in coal tar, from which it is extracted as salts of alkali metals, as well as in certain essential oils (for example, oil of jasmine). Along with skatole (3-methyl-indole), it is found in the intestines of human beings and mammals.

Many indole derivatives, for example, 3-indoleacetic acid (heteroauxin A, a growth substance), serotonin, and reserpine, are biologically active. Indole is a raw material for synthesizing heteroauxin and tryptophane, and is used in the perfumery industry to improve and strengthen the scents of flower essences.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Kobayashi, "Hyrtimomines, indole alkaloids from Okinawan marine sponges Hyrtios spp," Tetrahedron, vol.
Therefore, the aim of this current study is to evaluate effect of the detoxification herbal formula on transport of indole alkaloids in Caco-2 cells monolayer.
Among natural products, indole alkaloids represent an interesting class of compounds that contribute greatly to the therapeutic arsenal in malaria treatment [59].
Sarpagine and related indole alkaloids have shown very diverse and interesting biological properties that are widely dispersed in 25 plant genera, principally in Apocynaceae.
Don is a pantropical plant widely studied by pharmacognosists that contains about 130 terpenoid indole alkaloids (van Der Heijden et al.
The most important group of phytochemicals found in this plant are indole alkaloids. Over 50 different indole and indoline alkaloids have been isolated in this plant.
The topics include psychopharmacological indole alkaloids from terrestrial plants, the phytochemistry of Mitragyna speciosa, detecting mitragynine and its analogs, the kratom experience from first-hand reports, and abuse and addiction potential.
The plant has more than 70 types of alkaloids (mostly monoterpenes indole alkaloids), and some known to be effective in treating various types of cancer including breast and lung cancer, uterine cancer, melanomas, and Hodgkin's and non-Hodgkin's Lymphoma (El-Sayed A, as cited by Goyal, et al.
The indole alkaloids and terpenoids isolated from the roots, stem bark, fruits, and leaves possess cytotoxic, anti-implantation, and antioxidant properties [6-8].