Indole

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indole

[′in‚dōl]
Also known as 2,3-benzopyrrole.
(biochemistry)
C6H4-(CHNH)CH A decomposition product of tryptophan formed in the intestine during putrefaction and by certain cultures of bacteria.
(organic chemistry)
Carcinogenic, white to yellowish scales with unpleasant aroma; soluble in alcohol, ether, hot water, and fixed oils; melt at 52°C; used as a chemical reagent and in perfumery and medicine.

Indole

 

(2, 3-benzopyrrole), colorless crystals with an unpleasant odor. Melting point, 52°C; boiling point, 254°C. It is soluble in hot water and organic solvents. Indole is present in coal tar, from which it is extracted as salts of alkali metals, as well as in certain essential oils (for example, oil of jasmine). Along with skatole (3-methyl-indole), it is found in the intestines of human beings and mammals.

Many indole derivatives, for example, 3-indoleacetic acid (heteroauxin A, a growth substance), serotonin, and reserpine, are biologically active. Indole is a raw material for synthesizing heteroauxin and tryptophane, and is used in the perfumery industry to improve and strengthen the scents of flower essences.

References in periodicals archive ?
As a continuation of our interest in catalyst of supported mesoporous material in the organic synthesis [21, 22], herein, we reported isatins as the electrophiles to react with indoles using PWA/MCM-41 as catalyst at room temperature for the synthesis of 3,3-di(indolyl)indolin-2-ones.
As already mentioned, a number of studies have highlighted the capacity of AhR to respond to indolyl metabolites, including indoxyl-3-sulfate, 6-formylindolo[3,2b]carbazole, kyneurenine, kynurenic acid, tryptamine, indole-3-acetate, and dietary indoles (indole-3-carbinol and 3,3'-diindolylmethane from the Cruciferous vegetables), thus positioning the AhR as a candidate indole receptor [11, 15, 43, 44].
Phenols and indoles: Slurry samples were centrifuged at 4.000 rpm for 20 min at 20[degrees]C.
Por tanto la diferencia entre laicos y religiosos no consiste en la secularidad de unos, los laicos, frente a la no secularidad de los religiosos; sino en la secularidad laical (indoles saecularis) como diversa de la consagracion religiosa (consecratio) que modaliza la secularidad de los religiosos.
These brominated indole precursors are stored as choline ester salts in the hypobranchial glands of Muricidae (Baker & Sutherland 1968, Benkendorff 2013).
Se seleccionaron bacterias, aisladas del interior de la raiz, la rizosfera y la superficie de los tuberculos, productoras de diferentes concentraciones de indoles totales/ml, para determinar su efecto promotor o deletereo en el crecimiento vegetal.
Among the abnormal indoles described above, we focused on the 6-substituted indoles (7, 8) formed from 2-methoxyphenylhydrazone (5).
Indole, a potent basic pharmacodynamic nucleus, has been reported to possess a wide variety of biological properties viz., anti-inflammatory [1-3], anticonvulsant [4], cardiovascular [5], antibacterial [6].
Voafinidine and voalenine, a novel indoles of the aspidosperma alkaloids from Tabernaemontana.
Additionally, these packets also contain phytonutrients such as sulforaphane and indoles (in cruciferous vegetables) and ellagic acid (in strawberries), which promote healthy cell function and development.