Indole

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indole

[′in‚dōl]
Also known as 2,3-benzopyrrole.
(biochemistry)
C6H4-(CHNH)CH A decomposition product of tryptophan formed in the intestine during putrefaction and by certain cultures of bacteria.
(organic chemistry)
Carcinogenic, white to yellowish scales with unpleasant aroma; soluble in alcohol, ether, hot water, and fixed oils; melt at 52°C; used as a chemical reagent and in perfumery and medicine.

Indole

 

(2, 3-benzopyrrole), colorless crystals with an unpleasant odor. Melting point, 52°C; boiling point, 254°C. It is soluble in hot water and organic solvents. Indole is present in coal tar, from which it is extracted as salts of alkali metals, as well as in certain essential oils (for example, oil of jasmine). Along with skatole (3-methyl-indole), it is found in the intestines of human beings and mammals.

Many indole derivatives, for example, 3-indoleacetic acid (heteroauxin A, a growth substance), serotonin, and reserpine, are biologically active. Indole is a raw material for synthesizing heteroauxin and tryptophane, and is used in the perfumery industry to improve and strengthen the scents of flower essences.

References in periodicals archive ?
Interesting synthetic transformations/rearrangements were discovered including the high yield fragmentation of the hexacyclic 16-epi-19-S-vindolinine to a tricyclic indole.
Phenols and indoles were analyzed using a GC (6890N, Agilent, USA) equipped with DB-1 column (30 m x 0.
37) <<Nomine laicorum in hoc Codice intelleguntur christifideles, quibus indoles saecularis propia et specialis est quique in saeculo viventes missionem Ecclesiae participant neque in ordine sacro constituti neque statui religioso ascripti sunt>> (CCEO, canon 399).
These brominated indole precursors are stored as choline ester salts in the hypobranchial glands of Muricidae (Baker & Sutherland 1968, Benkendorff 2013).
Se seleccionaron bacterias, aisladas del interior de la raiz, la rizosfera y la superficie de los tuberculos, productoras de diferentes concentraciones de indoles totales/ml, para determinar su efecto promotor o deletereo en el crecimiento vegetal.
Among the abnormal indoles described above, we focused on the 6-substituted indoles (7, 8) formed from 2-methoxyphenylhydrazone (5).
Reaction of indole and 2-(chloromethyl)-3-methyl-4-(2,2,2-trifluoroethoxy) pyridine hydrochloride (I), using sodium hydride as base yielded the new fluoro-containing indole (II) i.
It has also been suggested that these five enzymes relate to the biosynthesis of terpenoid indole alkaloids of T.
Vegetables in the broccoli family contain natural chemical compounds called flavones, indoles, and isothiocyanates, which are thought to have cancer-fighting properties, says McCullough.
Cabbage contains indole-3-carbinole (I3C), sulforaphane and indoles, which are thought to help the body's antioxidant mechanisms.
THINLY-SLICED red cabbage is a good source of vitamin C and a group of phytochemicals called indoles.