Indole

(redirected from Indolic)
Also found in: Dictionary, Medical.

indole

[′in‚dōl]
Also known as 2,3-benzopyrrole.
(biochemistry)
C6H4-(CHNH)CH A decomposition product of tryptophan formed in the intestine during putrefaction and by certain cultures of bacteria.
(organic chemistry)
Carcinogenic, white to yellowish scales with unpleasant aroma; soluble in alcohol, ether, hot water, and fixed oils; melt at 52°C; used as a chemical reagent and in perfumery and medicine.

Indole

 

(2, 3-benzopyrrole), colorless crystals with an unpleasant odor. Melting point, 52°C; boiling point, 254°C. It is soluble in hot water and organic solvents. Indole is present in coal tar, from which it is extracted as salts of alkali metals, as well as in certain essential oils (for example, oil of jasmine). Along with skatole (3-methyl-indole), it is found in the intestines of human beings and mammals.

Many indole derivatives, for example, 3-indoleacetic acid (heteroauxin A, a growth substance), serotonin, and reserpine, are biologically active. Indole is a raw material for synthesizing heteroauxin and tryptophane, and is used in the perfumery industry to improve and strengthen the scents of flower essences.

References in periodicals archive ?
Yield: Colorless crystalline solid (66 %); MP: 219-220 AdegC; IR vmax (KBr) cm-1: 3450 (indolic N-H), 2910, 2810 (C-H), 1615-1400 (aromatic C=C) and 1126 (C-O); EI-MS m/z (rel.
(17.) Glickmann E, Dessaux Y A critical examination of the specificity of the Salkowski reagent for indolic compounds produced by phytopathogenic bacteria.
Dessaux 1995.A critical examination of the specificity of the salkowski reagent for indolic compounds produced by phytopathogenic bacteria.
Synthesis and Bioactivity of Secondary Metabolites from Marine Sponges Containing Dibrominated Indolic Systems.
Analyses performed with other indolic structures have shown that [ONOO.sup.-] reacts preferentially with 3 substituted indoles such as Trp derivatives rather than with unsubstituted indoles; and the most important products observed at physiological pH are 1-nitrosotryptophan derivatives kynurenines/kynuramines obtained by opening of the pyrrole ring [53].
This microorganisms are capable to synthetize plant growth regulators as indolic compounds (Patten and Glick, 2002; Cassan et al., 2009), defined as a group of organic substances with an important role in cell division, elongation, differentiation, development and growth of roots, tropism regulation and adult plant structure (Woodward and Bartel, 2005).
Dessaux, "A critical examination of the specificity of the Salkowski reagent for indolic compounds produced by phytopathogenic bacteria," Applied and Environmental Microbiology, vol.
The composition's overall warmth suggests the oddly familiar indolic dirt and sweetness of jasmine, the fragility of layered sweetness and earth.
Enumeration of human colonic bacteria producing phenolic and indolic compounds: effects of pH, carbohydrate availability and retention time on dissimilatory aromatic amino acid metabolism.
Scytonemin is a novel dimeric molecule of indolic and phenolic subunits with a molecular weight of 544g/mol It is a photestable molecule with broad-spectrum absorption encompassing the entire region from 325-425 with a max of 375nm!