Indole

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indole

[′in‚dōl]
Also known as 2,3-benzopyrrole.
(biochemistry)
C6H4-(CHNH)CH A decomposition product of tryptophan formed in the intestine during putrefaction and by certain cultures of bacteria.
(organic chemistry)
Carcinogenic, white to yellowish scales with unpleasant aroma; soluble in alcohol, ether, hot water, and fixed oils; melt at 52°C; used as a chemical reagent and in perfumery and medicine.

Indole

 

(2, 3-benzopyrrole), colorless crystals with an unpleasant odor. Melting point, 52°C; boiling point, 254°C. It is soluble in hot water and organic solvents. Indole is present in coal tar, from which it is extracted as salts of alkali metals, as well as in certain essential oils (for example, oil of jasmine). Along with skatole (3-methyl-indole), it is found in the intestines of human beings and mammals.

Many indole derivatives, for example, 3-indoleacetic acid (heteroauxin A, a growth substance), serotonin, and reserpine, are biologically active. Indole is a raw material for synthesizing heteroauxin and tryptophane, and is used in the perfumery industry to improve and strengthen the scents of flower essences.

References in periodicals archive ?
Chondriamides A and B, new indolic metabolites from the red alga Chondria sp.
In the present study, the production of indolic compounds with tryptophane at 0.
was performed using 7-methoxyindole (6) as a nucleophile, two kinds of the expected indolic dimer (23, 24) were obtained (Fig.
In spite of the large diversity of the molecules which have been tested, it is interesting to note that the ones active against Plasmodium are all indole derivatives (and one is both indolic and aminoimidazolic).
Most affected individuals also excrete excessive amounts of indolic compound, which originate in the gut from bacterial degradation of unabsorbed tryptophan (1).
1] area are attributed to the stretching vibrations (O-H and N-H) of the carboxylic acid, phenolic and aromatic amino functions presents in the indolic and pyrrolic systems.
Production of auxin and other indolic and phenolic compounds by Paenobacillus polymyxa strains isolated from different proximity to plant roots.
Oxidation kinetics of phenolic and indolic compounds by ozone: applications to synthetic and real swine manure slurry, Wat.
Bolognani-Fantin and Ottaviani (1981) observed additionally that the cells with fine acidophilic granules react positively to phenolic and indolic substances, which are considered as "Tyrian Purple" precursors.
determination of six indolic compounds, including melatonin, in rat pineal using high-performance liquid chromatography with serial fluorimetric-electrochemical detection.