infiltrate

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Related to infiltrates: corneal infiltrates

infiltrate

1. Pathol any substance that passes into and accumulates within cells, tissues, or organs
2. Pathol a local anaesthetic solution injected into the tissues to cause local anaesthesia

Infiltrate

 

an accumulation in bodily tissues of cellular elements admixed with blood and lymph. Inflammatory and tumorous infiltrates occur most often.

An inflammatory infiltrate consists chiefly of polymorphonuclear leukocytes (suppurative infiltrate), erythrocytes (hemorrhagic infiltrate), lymphoid cells (round cell infiltrate), and histiocytes and plasma cells (histiocyte-plasma cell infiltrate). These infiltrates may be resolved, may liquefy, or may undergo sclerosis and form caverns, abscesses, scars, and so forth.

A tumorous infiltrate consists of tumor cells of different kinds (carcinoma, sarcoma); it is a manifestation of the infiltrating growth of a tumor. When an infiltrate forms, the tissue enlarges, changes color, and becomes harder and sometimes painful. In surgical practice, an infiltrate is an induration that develops in tissues when they become saturated with an anesthetic.

V. V. SEROV

References in periodicals archive ?
Whether these inflammatory infiltrates exist in the brain samples of MTLE-HS patients with other neuronal membrane antibodies requires to be further studied.
The number of infiltrates that occurred on the medical unit was 11 pre-implementation and 5 post-implementation; surgical unit was 16 pre-implementation and 6 post-implementation.
In BL leprosy, diffuse infiltration of the dermis, except for narrow subepidermal zone (grenz zone), was seen in 88.88% cases, in addition to macrophage predominance of infiltrate in 83.33% cases and AFB that stained positively in 72.22% cases by modified ZN stain, while the sensitivity of bacilli detection increased to 83.33% when stained with modified Fite stain.
This dense inflammatory infiltrate may lead pathologists to misdiagnose ICN as lymphoma, especially in older patients.
The patient's symptoms are also important when assessing corneal infiltrates. The patient should be asked to grade the severity of the pain and also asked if they have photophobia, a watery eye or a sticky discharge.
These OB lesions were associated with mild perivascular mononuclear cell infiltrates surrounding venules and arterioles and limited to the vascular adventitia.
The patient underwent a second biopsy, which showed a dense infiltrate of small to large transformed lymphocytes, some plasma cells, and very few eosinophils.
Keratinocyte hyperproliferation, condensed dermal collagen, and mononuclear perivascular infiltrate increased with lymphedema stage, which suggested progressive chronic inflammation and fibrosis.
Immunohistochemical (IHC) staining for SFG Rickettsia demonstrated rickettsiae and rickettsial antigens in sections of heart, spleen, and kidney localized within and around vascular endothelial cells and reticuloendothelial cells, predominantly in areas associated with perivascular mononuclear inflammatory infiltrates (Figure 2).
Multiple tissues were examined from the hatchling alligator, and lesions differed from the previous submissions on the basis of cellular composition of the inflammatory cell infiltrates. Lymphoplasmacytic perivascular cuffs were present throughout the brain and meninges (Figure 1).
An opportunistic infection or a neoplastic infiltrate was the most probable cause.
Several chest X-rays were nondiagnostic; however, after 24 days of granulocytopenia, another computerized tomography scan revealed interstitial and patchy lung infiltrates. Because of persistent fever and newly developing lung infiltrates under broad-spectrum antibiotic therapy, invasive fungal infection was suspected, and conventional amphotericin B was administered (1 mg/kg/d).