insulin-like growth factor

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insulin-like growth factor

[¦in·sə·lən ‚lik ′grōth ‚fak·tər]
(biochemistry)
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Characterization of the acid-labile subunit of the growth hormone-dependent insulin-like growth factor binding protein complex.
Structure of the Mr 140,000 growth hormone-dependent insulin-like growth factor binding protein complex: determination by reconstitution and affinity-labeling.
Some structural and functional properties of insulin-like growth factor binding proteins (IGF-BP 1-6) IGF-BP-1 IGF-BP-2 IGF-BP-3 Gene location 7p14-p12 2q33-q34 7p14-p12 (chromosome) (a) Amino acids 234 289 264 Cysteine rich + + + N-region Cysteine rich + + + C-region Central L + + + domain Glycosilation - - N-linked Phosphorylation + - + Proteolysis + serine PAPP-A (e), (protease) protease (d) MMPs (f), PSA (g), cathepsin-D Synthesized by liver, maternal hepatocytes, liver, specific placenta epithelial subset of cells mesenchimal cells Expressed in amniotic fluid serum serum Binding to cell surface cell surface cell surface (RGD) (h) (RGD) (h), proteins ECM (i) (receptors?
The proteolysis of insulin-like growth factor binding proteins in ovine uterine luminal fluid.
Large variation in steroid concentrations and insulin-like growth factor binding proteins exists among individual small antral follicles collected from within cows at random stages ofthe estrous cycle.
A previous microarray experiment identified hepatic insulin-like growth factor binding protein 1 (IGF BP1) gene expression as consistently changed in correlation with serum corticosterone levels.
Physiologic and clinical relevance of the insulin-like growth factor binding proteins [Review].
Regulation of gene expression of rat insulin-like growth factor binding proteins 1 and 2.
The cloning and expression of the baboon acid-labile subunit of the insulin-like growth factor binding protein complex.
Plasma growth hormone, insulin-like growth factor I, and insulin-like growth factor binding proteins in pigs with divergent genetic merit for postweaning average daily gain.
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