integral membrane protein


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Related to integral membrane protein: Peripheral protein

integral membrane protein

[¦int·i·grəl ′mem‚brān ‚prō‚tēn]
(cell and molecular biology)
A protein that is firmly anchored in the plasma membrane via interactions between its hydrophobic domains and the membrane phospholipids. Also known as intrinsic protein.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The integral membrane protein, ponticulin, acts as a monomer in nucleating actin assembly.
Synaptophysin is a major integral membrane protein found in clear, small synaptic vesicles (SSVs) present in the mammalian spinal cord and retina, at neuromuscular junctions, and in the adrenal medulla (Wiedenmann and Franke, 1985).
In these lipids domains, cholesterol increases the order of lipid-acyl chains, increasing the local membrane thickness and limiting the type of integral membrane proteins located on this hydrophobic environment.
Caveolins are integral membrane proteins with molecular weight of 21 - 24 kDa, and as the scaffold structure, they recruit a lot of signal molecules.
Principles governing amino acid composition of integral membrane proteins: Applications to topology prediction.
integral membrane proteins, are thus specialized in detecting extra cellular signals and translating the information to the cell, allowing a response.