The cells are connected to each other end-to-end through highly specialised regions called the intercalated discs
Ablation of mXin[alpha] gene, encoding an intercalated discs
protein (1), results in cardiac hypertrophy and cardiomyopathy with a reduction in connexin 43 expression (2).
As in the vertebrate myocardium, the cellular unit of molluscan heart muscle is a mononucleated muscle cell linked to its neighbors by intercalated discs
(North, 1963; Watts et al.
Subsequent microscopic analysis of the rabbits' hearts showed the transplanted cells had developed intercalated discs
, "a distinctly cardiac feature" that is involved in transferring from cell-to-cell the electrical charge that powers the heartbeat, said investigator Doris Taylor, Ph.