interleukin-13

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interleukin-13

[‚in·tər¦lük·ən ′thər‚tēn]
(immunology)
A cytokine produced by activated T lymphocytes that inhibits inflammatory cytokine production induced by bacterial endotoxin and stimulates gamma-interferon production by natural killer cells, enhancing the effect of interleukin-2. Abbreviated IL-13.
References in periodicals archive ?
The contract has been signed for Demira to receive exclusive rights to lebrikizumab, a monoclonal antibody targeting interleukin 13 (IL-13), for atopic dermatitis and all other indications.
The scientists report that when these cells were exposed to a well-known molecular activator of EoE -- an immune hormone called Interleukin 13 (IL-13) -- it caused dramatic up-regulation of CAPN14.
The scientists report that when these cells were exposed to a well-known molecular activator of EoE - an immune hormone called Interleukin 13 (IL-13) - it caused dramatic up-regulation of CAPN14.
Working with mice, Chawla s team discovered that the signaling molecules, called interleukin 4 and interleukin 13, activate cells known as macrophages, which in turn drive the fat conversion.
Interleukin 13 stimulation of IL-13R[alpha]1 was mediated via a leukocyte-dependent and partially IL-4R[alpha]-dependent pathway.
Hershey, PA) announced the issuance of United States Patent 6,884,603 for its genetically modified, mutated Interleukin 13 (IL-13) technology platform for the treatment of malignant glioma, a brain tumor (17,500 people annually; $200 million annual market).
Using these mice, we found that ILC2 cells were the major population in the skin that produced interleukin 13, a molecule that has been linked to a number of allergic diseases, including eczema.
23,37-39) Interleukin 13 regulates the humoral response by driving the proliferation and survival of B cells and triggering immunoglobulin class switching.
The studies that NeoPharm has performed in animals and in ex-vivo human tissue have shown that the receptors for interleukin 13 (IL13) are significantly over-expressed in pulmonary fibroblasts.