The scientists report that when these cells were exposed to a well-known molecular activator of EoE - an immune hormone called Interleukin 13
(IL-13) - it caused dramatic up-regulation of CAPN14.
The scientists report that when these cells were exposed to a well-known molecular activator of EoE -- an immune hormone called Interleukin 13
(IL-13) -- it caused dramatic up-regulation of CAPN14.
Working with mice, Chawla s team discovered that the signaling molecules, called interleukin 4 and interleukin 13
, activate cells known as macrophages, which in turn drive the fat conversion.
stimulation of IL-13R[alpha]1 was mediated via a leukocyte-dependent and partially IL-4R[alpha]-dependent pathway.
suppresses cytokine production and stimulates the production of 15-HETE in PBMC.
Hershey, PA) announced the issuance of United States Patent 6,884,603 for its genetically modified, mutated Interleukin 13
(IL-13) technology platform for the treatment of malignant glioma, a brain tumor (17,500 people annually; $200 million annual market).
Using these mice, we found that ILC2 cells were the major population in the skin that produced interleukin 13
, a molecule that has been linked to a number of allergic diseases, including eczema.
23,37-39) Interleukin 13
regulates the humoral response by driving the proliferation and survival of B cells and triggering immunoglobulin class switching.
The studies that NeoPharm has performed in animals and in ex-vivo human tissue have shown that the receptors for interleukin 13
(IL13) are significantly over-expressed in pulmonary fibroblasts.
IL-13ra1 is a receptor chain mediating the action of interleukin 13
(IL-13) and interleukin 4 (IL-4), two cytokines investigated for their role as mediators of allergic reactions and for their anti-inflammatory action.
The targeting component consists of interleukin 13
(IL13) an immune regulatory cytokine (normally made by cells of the immune system).
TNX-650 targets Interleukin 13
, an important growth factor for malignant Hodgkin's lymphoma cells.