interleukin-4

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interleukin-4

[‚in·tər′lük·ən ′fȯr]
(immunology)
A cytokine that is capable of a variety of activities, such as induction of proliferation by T cells, mast cells, megakarocytes, and erythroid precursors; induction of antibody secretion by B cells; and potentiation of the proliferation of mast cells. Abbreviated IL-4.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
ASLAN004 is a fully human monoclonal antibody that targets the IL-13 receptor alpha1 subunit and has demonstrated inhibition of interleukin 4 and interleukin 13 in preclinical investigations.
The product is a fully human monoclonal antibody that targets the IL-13 receptor alpha 1 subunit (IL-13R alpha 1) and potently inhibits interleukin 4 (IL-4) and interleukin 13 (IL-13).
Loughlin, "Common variants within the interleukin 4 receptor a gene (IL4R) are associated with susceptibility to osteoarthritis," Human Genetics, vol.
Schlesinger, "Kinetics of the pleiotropic effect of interleukin 4 on the surface properties of human BLymphoma cells," Leukemia and Lymphoma, vol.
They do know, for example, that interleukin 4 stimulates a TH2 response and the subsequent production of antibodies.
ASLAN004 is a fully human monoclonal antibody that targets the IL-13 receptor alpha1 subunit and potently inhibits interleukin 4 and interleukin 13.