interleukin-8

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interleukin-8

[‚in·tər¦lük·ən ′āt]
(immunology)
A group of peptides produced by a variety of cell types, which activate and recruit polymorphonuclear leukocytes in the inflammatory process, and are probably involved in initiation of labor and delivery in pregnant women. Abbreviated IL-8.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
C-X-C Chemokine Receptor Type 2 (CDw128b or GRO/MGSA Receptor or High Affinity Interleukin 8 Receptor B or IL8 Receptor Type 2 or CD182 or CXCR2) pipeline Target constitutes close to 16 molecules.
C-X-C Chemokine Receptor Type 2 (CDw128b or GRO/MGSA Receptor or High Affinity Interleukin 8 Receptor B or IL8 Receptor Type 2 or CD182 or CXCR2) - CXCR2 or Interleukin 8 receptor, beta is a chemokine receptor.
Keywords: Interleukin 8, dipping tobacco, association, biomarker, oral cancer, ELISA
Interleukin 6 and interleukin 8 are the much studied cytokines as they are essential mediators of cancer development and powerful activators of apoptotic and anti-apoptotic signaling cascade.16 IL-8 is found to stimulate angiogenesis, influence tissue remodeling, leukocyte chemotaxis, dysregulated cell cycle, suppressed immune system and regulating of cell proliferation and differentiation.17 Various stimuli for example chemical and environmental stresses including chemotherapy and hypoxia, proinflammatory cytokines like TNF-[alpha] and IL-1, hormones and bacterial and viral products are known to regulate the manifestations of IL-8.18
Previous studies have shown that levels of the cytokines interleukin 6, interleukin 8, and granulocyte colony-stimulating factor (G-GSF) are elevated in the amniotic fluid and cervical secretions of women with intrauterine infection, compared with those without infection, said Dr.
In a study aimed at determining if interleukin 8 and G-CSF held the same predictive value, Dr.