interleukin-6


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interleukin-6

[‚in·tər¦lük·ən ′siks]
(immunology)
A cytokine derived from activated T lymphocytes that has many functions, including induction of B-cell growth; induction of B-cell differentiation and antibody production; induction of differentiation and proliferation of T cells; synergistic induction with IL-3 of hematopoietic cell growth; and induction of hepatocyte secretion of acute-phase inflammatory proteins. Abbreviated IL-6.
References in periodicals archive ?
But remarkably, this effect was abolished in participants who were also treated with tocilizumab, a drug that blocks interleukin-6 signaling and is currently approved for the treatment of rheumatoid arthritis.
But Wedell-Neergaard and co-senior study author Helga Ellingsgaard suspected that interleukin-6 could also play an important role because it regulates energy metabolism, stimulates the breakdown of fats in healthy people, and is released from skeletal muscle during exercise.
Relationship between rs1800795 single nucleotide polymorphisms and serum interleukin-6 level in different neuroblastoma-risk groups and MYCN gene amplification status groups
The mean level of interleukin-6 was 49.65+-3.04 in Group B and 104.14+-76.03 in Group A, with significant inverse correlation with endometrial thickness (p<0.001).
Interleukin-6 (IL-6) is a multi-functional cytokine that participates in both physiological and pathological processes6.
Tumor necrosis factor-[alpha] and interleukin-6 gene polyporphism association with susceptibility to celiac disease in Italian patients.
Amiot, "The role of interleukin-6 and interleukin-6/interleukin-6 receptor-alpha complex in the pathogenesis of multiple myeloma," European Cytokine Network, vol.
The median serum interleukin-6 concentration was lower among the female participants compared to the male counterparts, with median values of 3.74pg/mL (0.00-171.00 pg/mL) and 2.36pg/mL (0.00-45.31 pg/mL) among the male and female participants, respectively (p = 0.88, Mann-Whitney U test).
Circulatory IL-6 and tumor necrosis factor - alpha have been shown to be highly significantly associated with chronic periodontitis, as their concentration declined with periodontal treatment.4 Positive affiliation of interleukin-6 in patients with unstable angina5 has also been reported.
This article will explain what Life Extension[R] is doing to accelerate restoration of immune competence in aging humans today, including suppressing deadly interleukin-6 levels.
Keywords: Hypoxic ischemic encephalopathy (HIE) creatine monohydrate interleukin-6 (IL-6) interleukin-18 (IL- 18) enzyme linked immunosorbent assay (ELISA).
: ABSTRACTObjective: This study aims to explore the effects of soluble interleukin-6 receptor (IL-6R) on the clinical diagnosis and treatment of autoimmune rheumatic disease (ARD) patients.Methods: Sixty-eight ARD patients enrolled in our hospital recently were selected the IL-6R levels of whom were detected by double-antibody sandwich ELISA method and compared with the IL-6 levels of normal subjects.