interleukin-8


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interleukin-8

[‚in·tər¦lük·ən ′āt]
(immunology)
A group of peptides produced by a variety of cell types, which activate and recruit polymorphonuclear leukocytes in the inflammatory process, and are probably involved in initiation of labor and delivery in pregnant women. Abbreviated IL-8.
References in periodicals archive ?
Salivary level of interleukin-8 in oral precancer and oral squamous cell carcinoma.
* The report provides a snapshot of the global therapeutic landscape for C-X-C Chemokine Receptor Type 2 (CDw128b or GRO/MGSA Receptor or High Affinity Interleukin-8 Receptor B or IL-8 Receptor Type 2 or CD182 or CXCR2)
(25.) Zouboulis C, Katsantonis J, Keteler R et al: Adamantiades-Behcet's disease: interleukin-8 is increased in serum of patients with active oral and neurological manifestations and is secreted by small vessel endotelial cells.
Global Markets Direct's, 'C-X-C Chemokine Receptor Type 1 (CDw128a or High Affinity Interleukin-8 Receptor A or IL-8 Receptor Type 1 or CD181 or CXCR1) - Pipeline Review, H1 2016', provides in depth analysis on C-X-C Chemokine Receptor Type 1 (CDw128a or High Affinity Interleukin-8 Receptor A or IL-8 Receptor Type 1 or CD181 or CXCR1) targeted pipeline therapeutics.
The expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX)-2 and intercellular adhesion molecule-1 (ICAM-1), and the release of nitric oxide, prostaglandin (PG)E(2) and interleukin-8 (IL-8) were determined.
1379) examined signaling events involved in the expression of the inflammatory gene interleukin-8 (IL-8) in human airway epithelial cells (HAECs) exposed to ambient PM collected in an urban area of Mexico.
The proinflammatory cytokine interleukin-8 was diminished on the treated sides.
Curiously, says Berger, fusin resembles a molecule that binds to a chemokine called interleukin-8. Chemokines are a small family of proteins, some of which have recently been found to suppress HIV infection (SN: 12/9/95, p.
Interleukin-8 is a principle neutrophil chemoattractant and activator in humans.
In the January 2005 issue of the Annals of Neurology, Carlos Pardo, an assistant professor of neurology and pathology at the Johns Hopkins University School of Medicine, and his colleagues report finding high levels of inflammatory cytokines (interleukin-6, interleukin-8, and interferon-[gamma]) in the cerebrospinal fluid of autistic patients.
To exemplify the new procedure, Kent and his crew cobbled together two large peptides -- one with 33 amino acids and the other with 39 -- to create an exact replica of human interleukin-8, an immune system protein with 72 amino acids.