intermediate filament

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intermediate filament

[‚int·ər′mēd·ē·ət ′fil·ə·mənt]
(cell and molecular biology)
Any of several classes of cell-specific cytoplasmic filaments of 8-12 nanometers in diameter; protein composition varies from one cell type to another.
References in periodicals archive ?
Peripherin, a new member of the intermediate filament protein family.
Interactions of intermediate filament protein synemin with dystrophin and utrophin.
A rapid method for the large scale purification of the intermediate filament protein vimentin by single-stranded DNA-cellulose affinity chromatography.
Intermediate filament proteins, or nanofilament proteins as they are sometimes called, are important stress proteins that in many cell types act as crisis command centers in times of cellular stress and emerge as interesting targets in many diseases.
The keratins are intermediate filament proteins and are important for integrity and mechanical stability of epithelial cells with the largest number of keratin genes expressed in skin.
Krombauer Soska et al., "Acute intrastriatal administration of quinolinic acid provokes hyperphosphorylation of cytoskeletal intermediate filament proteins in astrocytes and neurons of rats," Experimental Neurology, vol.
In addition, several intermediate filament proteins such as vimentin and annexin, as well as histone H1.2 and H2A, were down-regulated in the high producer.
The [alpha]-helical rod domain is critical for the assembly of intermediate filament proteins into filaments and contains all the information necessary for assembly, while the variant end domains play accessory roles in filament assembly and interaction with other proteins and cell structures.

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