Development of c-kit immunopositive interstitial cells
of Cajal in the human stomach.
Liu, "Exogenous stem cell factor improves interstitial cells
of cajal restoration after blockade of c-kit signaling pathway," Scandinavian Journal of Gastroenterology, vol.
Mohamed, "A seasonal and age-related study of interstitial cells
in the pineal gland of male viscacha (Lagostomus maximus maximus)," The Anatomical Record, vol.
of Cajal are a group of cells interacting with enteric neurons and smooth muscle cells.
Hirst, "Role of interstitial cells
of Cajal in neural control of gastrointestinal smooth muscles," Neurogastroenterology & Motility, vol.
However, thickness of testicular capsule and percentage area of interstitial cells
showed a reverse trend with significantly (Pless than 0.01) highest values found during resting phase (Table 2; Fig.
It is believed that GIST is transformed from the interstitial cell
of Cajal, which is an important pacemaker cell that regulates smooth muscle contraction in the gastrointestinal tract.
For the vehicle mice (0 Gy, nonhydrogen, (a)), the testes showed normal testes histoarchitecture with successive stages of spermatogenesis which include spermatogonia (SG), spermatocytes (SC), different stages of spermatids (SD), and spermatozoa (SP) surrounding a central lumen, and interstitial cell
(I) and basal membrane kept their normal morphology as well.
The origin of spontaneous contraction is believed to be associated with the activity of interstitial cells
of Cajal (ICCs).
Staining was more frequent and more intense in diabetic samples, which was confirmed by semiquantitative scoring of epithelial cells and interstitial cells
Kindblom and associates in 1998 demonstrated that the actual cell of origin of these tumors is a pluripotent mesenchymal stem cell programmed to differentiate into interstitial cells
of Cajal, the GI tract "pacemaker cells"--the cells responsible for initiating and co-coordinating GI motility.
Taken together, EP inhibits myofibroblast expansion and cytoskeletal proteins expression, accompany by the capacity of release collagen secretion, suggest that EP may disturb the process of renal interstitial cells
dedifferentiation into myofibroblasts.