Ischemia

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ischemia

[i′skē·mē·ə]
(medicine)
Localized tissue anemia as a result of obstruction of the blood supply or to vasoconstriction.

Ischemia

 

a local deficiency of blood; insufficient blood in an organ or tissue because of the narrowing or complete occlusion of the lumen of an afferent artery.

Transitory ischemia (like hyperemia) may result from physiological regulation of the blood supply, such as in reflex spasm of an artery caused by a mental factor (fright); the influence of pain, cold, chemical substances (epinephrine, ergotin), and biological stimuli (bacteria, toxins); the obstruction of an artery by a thrombus or embolus; constriction of the lumen of a blood vessel in connection with an atherosclerotic or inflammatory process in the wall; or compression of an artery by a tumor, scar, or foreign body. The aftereffects of ischemia depend on the degree of disruption of the blood flow, the rate of development and duration of the ischemia, the sensitivity of the tissue to oxygen deficiency, and the general condition of the body. Ischemia may end in complete restoration of the structure and function of the affected organ or tissue, but it also may lead to necrosis (infarct). The central nervous system and heart muscle are particularly sensitive to ischemia.

N. R. PALEEV

References in periodicals archive ?
Only a "chronic course" of the disease may differentiate venous from arterial intestinal ischemia.
The etiology of venous intestinal ischemia should be understood in terms of Virchow triad of stasis, vessel injury, and a hypercoagulable state.
Our study demonstrated that I-FABP levels, a strong indicator of intestinal ischemia, was elevated at the end of surgery in both CPB and 0PCAB groups.
In the critical care setting, the development of intestinal ischemia carries with it a mortality of between 67% and 80% (3).
The resulting intestinal ischemia creates free oxygen radicals.
Another parameter that can be used as an indicator of intestinal ischemia is I-FABP, which is characterized by being an early indicator.
We focused on intestinal ischemia and related indicators (particularly I-FABP) in patients who have undergone CPB.
We investigated only 51 patients who underwent heart surgery with or without CPB, and none developed clinical intestinal ischemia.
Systematic review and pooled estimates for the diagnostic accuracy of serological markers for intestinal ischemia.
Human intestinal fatty acid binding protein in peritoneal fluid is a marker of intestinal ischemia.