Ranaviruses, which belong to the family Iridoviridae
, have been detected in a wide range of amphibian populations in Europe (Martel et al., 2012), Australia (Speare and Smith, 1992), South America (Fox et al., 2006), North America (Souza et al., 2012) and Asia (He et al., 2002).
double-stranded DNA viruses from the family Iridoviridae
, which infect fish, amphibians, and reptiles, typically causing external and internal hemorrhaging and necrosis.
Ranavirosis is caused by ico-sahedral cytoplasmic DNA viruses that belong to the family Iridoviridae
, in particular by 4 species of Ranavirus: Frog Virus 3 (FV3), Bohle iridovirus, Ambystoma tigrinum virus, and a possible species Rana catesbeiana virus Z.
Viruses reported in marine shellfish include Herperviridae, Iridoviridae
, Papovaridae, Togaviridae, Retroviridae, Reviridae, and Paramyxoviridae.
Frog Virus 3 is a member of the family Iridoviridae
. The cascade of viral gene expression is divided into two stages, early and late, that take places within the nucleus and cytoplasm, respectively.
Six ORFs encode proteins with closest relatives in virus families such as Poxviridae and Iridoviridae