On the other hand, soy peptides and isoflavones
are biodegradable, environmentally friendly and non-toxic.
In this paper, MSPD has been successfully used for the extraction of the isoflavones
daidzein, genistein, and glycitein, as well as their glycosides daidzin, genistin, and glycitin, respectively, from different defatted soybean flours.
For 12 weeks in a randomized trial, 70 women aged 18 to 40 years with polycystic ovary syndrome were assigned to consume 50 mg per day of a soy isoflavone
supplement or a placebo.
genistein, daidzein, equol were measured in 24 h urine samples.
There is growing interest in using soy isoflavones
in diseases related to metabolic syndrome.
A growing body of epidemiological studies has revealed that the incidence of PCa is reduced in population with food rich in isoflavones
.[sup], Many studies have demonstrated that isoflavones
exert hormone-like effects [sup] and nonhormone-like effects involving inhibiting tyrosine kinases,[sup] modulation of cell proliferation, regulation of cell cycle, apoptosis, angiogenesis, and tumor cell metastasis,[sup] and our recent study found isoflavones
induced autophagy cell death by up-regulation of ULK1 level, especially increasing evidence has indicated that isoflavones
may be protective against the development of PCa.
The 66mg of isoflavone
that we use in this study is equivalent to eating an oriental diet, which is rich in soy foods."
Conclusion Soy isoflavones
supplementation 160 mg/day can lower total AV lesion.
belong to a family of nonnutritive compounds modulating a diversity of biological processes linked to carcinogenesis.
Qiu, "Soy-derived isoflavones
inhibit HeLa cell growth by inducing apoptosis," Plant Foods for Human Nutrition, vol.
Despite previous reports that soy isoflavones
have deleterious effects, they still are often used by postmenopausal women as an alternative to hormone therapy, according to study author, D.