Copper (II) sulfate pentahydrate (Merck, purity: 99%), isonicotinic acid
hydrazide (Fluka, purity: 99%), L-ascorbic acid (S.D.Fine Chemicals, purity: 99%) and sodium hydroxide (Thomas Baker, purity: 97.5%), polyvinylpyrrolidone (Aldrich, purity: 98-99%) were used without further purification.
The 3HP group was given once weekly, directly observed treatment with rifapentine (brand name Priftin; 900 mg) plus isoniazid (brand name Nydrazid, also known as isonicotinic acid
hydrazide or INH; 15-25 mg/kg) for 3 months.
The reaction occurred within 10 minutes by simply grinding hydrated copper acetate Cu[(CH).sub.3]C[O.sub.2].2[H.sub.2]O and isonicotinic acid
. The formation of a reaction product was indicated by a change in colour from green to blue and the characteristic odor of acetic acid, released as by-product.
Good examples of vitamin antagonists include isonicotinic acid
hydrazide (antagonist of pyridoxine), aminopterin (folate antagonist), dicumarol (vitamin K antagonist), and avidin (interferes with biotin absorption).
To exclude false UFC values, future measurements of UFC should include a chromatographic step in the cortisol assay (10), or investigators should use specific methods such as HPLC (11-13) or thin-layer chromatography/steroid derivatiza tion with isonicotinic acid
Stanica, Synthesis and structural studies of complexes of Cu, Co, Ni and Zn with isonicotinic acid
hydrazide and isonicotinic acid
(1-naphthylmethylene) hydrazide, J.
Sodium perchlorate (Analar grade; BDH), sodium hypochlorite solution (125 g/L, technical grade; APS Ajax Fine Chemicals), isonicotinic acid
(Sigma), 1,3-dimethylbarbituric acid (Fluka), and AG3-X4 anion-exchange resin (100-200 mesh, free base; Bio-Rad Laboratories) were used in the column method (11).
hydrazide is used for prevention and treatment of mycobacterium tuberculosis as first-line medication [10-12].
Determination of Isonicotinic Acid
Hydrazide [isoniazid] using N-bromosuccinimide.
Dianu, Investigation of Zn (II), Cd and Hg with Isonicotinic Acid
-1-H-indole-2,3-dione hydrazide system, Analele Universitatii Bucuresti-Seria Chimie.
Summary: A novel series of 1,2,4-triazolo[3,4-b][1,3,4]thiadiazole derivatives were synthesized from isonicotinic acid
as starting material using microwave method.
(linker) and oxalate ligands were successfully employed to coordinate Pr and Cu within the same metal-organic frame work (MOF).