Six reversed C-glycopeptidomimetics were prepared using Passerini reaction; a three components reaction of aldehyde, carboxylic acid and isonitrile to furnish amide ester linkage Scheme-1.
Passerini reaction was carried out at room temperature using sugar aldehyde 1b, different aliphatic acids (2a-2f) and isonitrile 3c in dichloromethane and stirred for 8 hours to overnight (vide experimental).
Miller, "[pi]-back-bonding in Bis(isonitrile
) complexes of rhodium(II) acetate: structural analogs for rhodium carbenoids," Organometallics, vol.
Inhibition of heme detoxification processes underlies the antimalarial activity of terpene isonitrile
compounds from marine sponges.
Already in the 1971 volume of Isonitrile
Chemistry  325 isocyanides were mentioned, and today approximately 3000 isocyanides are known.
Use of technetium-99m isonitrile
in assessing left ventricular perfusion and function at rest and during exercise in coronary artery disease, and comparison with coronary arteriography and exercise in thallium 201 SPECT imaging.
isocyanide or isonitrile
ion as shown in figure 1[refs.
Some of the patients underwent assessment of LV function by Technetium MIBI (Methoxy Iso Butyl Isonitrile
) scan after Adenosine stress.
Increased dense activity involvement especially on the left side of the neck, pathologically focally increased activity involvement in the right iliac wing and focally relatively increased activity involvement in the area compatible with the second lumbar spine were detected on Technetium-99m methoxyisobutyl isonitrile
(99mTc- MIBI) scintigraphy (Figure 4).
The volume of the Isonitrile
Chemistry  of 1971 already mentioned 325 isocyanide.
Uptake and kinetics of Tc-99m hexakis 2-methoxy isobuytl isonitrile
in benign and malignant lesions in the lungs.
Thus, substituted imidazo[1,2-b]pyrazole-7-carbonitrile 76 was prepared by cyclocondensation of aminopyrazolecarbonitrile 73 with 3,4dimethoxyphenyl isonitrile
74 and 2,4-dihydro-2-oxo-1Hbenzo[d][1,3]oxazine-7-carbaldehyde 75  Scheme 17).