Troschke et al., "Reconstitution of an apicoplast-localised electron transfer pathway involved in the isoprenoid
biosynthesis of Plasmodium falciparum," FEBS Letters, vol.
Interestingly, [C.sub.16]-[C.sub.23] aryl isoprenoids
were detected from extracts from solid bitumen from wells HB101, LG82, and YB101 in the western gas fields (Figure 5).
The first target molecules are part of the isoprenoid
family (including carotenoids) that may lead to the production of specialty ingredients, such as antioxidants and / or high-added value pigments, representing a market of hundreds of millions of dollars worldwide in applications such as cosmetics, food, feed and health.
In overcast skies the contribution of diffuse radiation to emission of isoprenoids
may be even larger and exceed the contribution of direct radiation.
Regulatory mechanism of HMGS in plants: HMGS participates in the synthesis of precursors of isoprenoids
and provides reactive substrates for HMGR.
Burke, Y.D., Stark, M.J., Roach, S.L., Sen, S.E., Crowell, P.L., 1997, Inhibition of pancreatic cancer growth by the dietary isoprenoids
farnesol and geraniol.
This may be explained by the antioxidant effects of simvastatin, as a result of inhibition of mevalonate pathway causing a significant reduction in the biosynthesis of important intermediates, like isoprenoids
, which act as a lipid attachment/anchoring for intracellular signaling molecules, particularly the inhibition of the small GTPase binding proteins whose proper membrane localization and function are dependent on isoprenylation.
A good example is Amyris Biotechnolgies, founded in 2003, which has been working on a class of hydrocarbons called isoprenoids
as a substitute for petrol.
Biosynthesis of isoprenoids
(carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a novel pyruvate/glyceraldehydes 3-phosphate non-mevalonate pathway in the green alga Scenedesmus obliquus.
Scientists and engineers in biochemistry, biotechnology, and related fields survey developments and prospects for producing biofuel molecules such as hydrogen, methane, ethanol, butanol, higher chain alcohols, isoprenoids
, and fatty acid derivatives by metabolically engineered microbes such as bacteria, yeast, and microalgae.
Goettingen, Germany, August 31, 2014 --(PR.com)-- Isoprenoids
in living organisms range in function from pigments and fragrances to vitamins and precursors of sex hormones.
Many organisms, including the parasite that causes malaria, make a class of molecules called isoprenoids
, which play multiple roles in keeping organisms healthy, whether plants, animals or bacteria.