Isoprenoids


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Isoprenoids

 

a large class of natural compounds formed in organisms from mevalonic acid. The latter is converted in the microsomes of the cells into “five-carbon fragments” with an isoprene skeleton. The biosynthesis of isoprenoids is a process of consecutive linking (condensation) of such five-carbon units into chains of various lengths. The doubling, cyclization, oxidation, reduction, and regrouping of such chains accounts for the extraordinary structural diversity of isoprenoids. The isoprenoids include terpenes and their derivatives, sterols, steroids, carote-noids, xanthophylls, and the polyisoprenoids—natural rubber and gutta-percha. A number of isoprenoids have great biological significance—many hormones of animals, plants, and lower organisms; certain vitamins; antibiotics; and attractants.

REFERENCES

Biosintez lipidov. Moscow, 1962.
Kosover, E. Molekuliarnaia biokhimiia. Moscow, 1964. (Translated from English.)
Biokhimiia rastenii. Moscow, 1968. (Translated from English.)
References in periodicals archive ?
The MP has been reported as a metabolic sequence modulated by isoprenoids (Mo and Elson 2004; Ong et al.
Thomitrems A and E, two indole-alkaloid isoprenoids from Penicillium crustosum Thom.
Whether these isoprenoids are synthesized de novo by the parasite or taken from the [host] medium is not yet definitively proven," Jomaa notes.
Natural product classes covered include carbohydrates, amino acids, peptides, proteins, nucleosides, nucleotides, nucleic acids, polyketides, isoprenoids, shikimic acid derivatives and alkaloids.
The NIH previously awarded Echelon five Phase I and two Phase II grants to prepare and market phosphoinositides and isoprenoids important in cell biology.
Emission of isoprenoids by plants: their role in atmospheric chemistry, response to the environment, and biochemical pathways.
All Biluo Co oil shale samples are characterized by the presence of n-alkanes, isoprenoids, terpanes and steranes.
his enzyme promotes the synthesis of a class of compounds, called isoprenoids, which are essential to life.
In: Cane (ed) Comprehensive natural products chemistry: isoprenoids.
The saponins--polar isoprenoids with important and diverse biological activities.
Many isoprenoids contribute to plants' distinctive flavors and fragrances.
Among the byproducts of cholesterol synthesis are proteins called isoprenoids, which in turn activate ras, another protein, that is responsible for cell division and survival, said Dr.