Isotonic Solutions

Isotonic Solutions

 

solutions with the same osmotic pressure; in biology and medicine, natural or artificially prepared solutions with the same osmotic pressure as that of the content of animal and plant cells, blood, and interstitial fluids.

In normally functioning animal cells the intracellular content is usually isotonic with the extracellular fluid. When there is severe disruption of the isotonicity of the solutions in a plant cell and its surrounding medium, water and dissolved substances are transferred freely into or out of the cell, which may lead to a disturbance of normal cell functions. As a rule, isotonic solutions are close to sea water in composition and concentration. For warm-blooded animals, a 0.9 percent solution of NaCl and a 4.5 percent solution of glucose are isotonic. Isotonic solutions that are close in composition, pH, buffering capacity, and other properties to blood serum are called physiological solutions (Ringer’s solution for cold-blooded animals; Ringer-Locke’s and Ringer-Tyrode’s solutions for warm-blooded animals). Compounds of high molecular weight (dextran, polyvinol) are introduced into isotonic hemosubstitutive solutions to create colloidal-osmotic pressure.

A. A. BULYCHEV and V. A. SOLOV’EV

References in periodicals archive ?
The exercise is followed by a series of questions to help students understand the concept of hypotonic, hypertonic, and isotonic solutions.
The other mediums such as isotonic solutions have a shelf life and therefore need restocking periodically.
If unable to re-implant store the tooth in isotonic solution i.
One of the advantages of ciclesonide is that, unlike most intranasal sprays currently available as isotonic solutions, ciclesonide is in a hypotonic saline solution, which is somewhat more tolerable to patients, he said.
David Parsons, MD, FAAP, FACS, a Board Certified ENT surgeon and recognized international authority on paranasal sinus disease stated, "Using nasal washes such as ENTsol(R) with a hypertonic saline solution produces a significant increase in ciliary flow and reduction in nasal swelling, while nasal wash solutions with isotonic solutions produce virtually no change.
The use of isotonic solutions should eliminate the incidence of these potentially catastrophic complications.
In September, the Company initiated commercial shipments of the Diva(TM) laparoscopic morcellator and the OPERA STAR SL(R), the first hysteroscope to allow the use of safer isotonic solutions, such as normal saline.
The ability to effectively use isotonic solutions during hysteroscopic procedures would markedly reduce the risk of serious electrolyte disturbances and their associated complications and could well become the standard of care due to its higher margin of safety," noted Richard Gimpelson, M.