Isotonic Solutions

Isotonic Solutions

 

solutions with the same osmotic pressure; in biology and medicine, natural or artificially prepared solutions with the same osmotic pressure as that of the content of animal and plant cells, blood, and interstitial fluids.

In normally functioning animal cells the intracellular content is usually isotonic with the extracellular fluid. When there is severe disruption of the isotonicity of the solutions in a plant cell and its surrounding medium, water and dissolved substances are transferred freely into or out of the cell, which may lead to a disturbance of normal cell functions. As a rule, isotonic solutions are close to sea water in composition and concentration. For warm-blooded animals, a 0.9 percent solution of NaCl and a 4.5 percent solution of glucose are isotonic. Isotonic solutions that are close in composition, pH, buffering capacity, and other properties to blood serum are called physiological solutions (Ringer’s solution for cold-blooded animals; Ringer-Locke’s and Ringer-Tyrode’s solutions for warm-blooded animals). Compounds of high molecular weight (dextran, polyvinol) are introduced into isotonic hemosubstitutive solutions to create colloidal-osmotic pressure.

A. A. BULYCHEV and V. A. SOLOV’EV

References in periodicals archive ?
However, recent studies have demonstrated that the tonicity of the enteral rehydration solution affects the level of water and electrolyte absorption, with hypotonic solutions resulting in better water absorption than isotonic solutions in children (RAUTANEN et al.
Here, we discuss the role played by isotonic solutions in facilitating bacterial reproduction.
Isotonic solutions may be contaminated by contact with another infected patient or by bacterial transmission from the environment, including via surface contact, invasive procedures, and as a bioaerosol through the air.
Plasma volume expansion is, therefore, achieved with lesser free water administration than with isotonic solutions.
Since administration of a hypertonic should lead to recruitment of extravascular fluids into the vascular compartment, HSS seems likely to produce a more rapid response and marked hemodynamic effects than isotonic solutions (Bleul et al.
Isotonic solutions are appropriate for patients suffering from extracellular fluid deficits such as in hemorrhaging or hypovolemic shock.
The exercise is followed by a series of questions to help students understand the concept of hypotonic, hypertonic, and isotonic solutions.
The other mediums such as isotonic solutions have a shelf life and therefore need restocking periodically.
One of the advantages of ciclesonide is that, unlike most intranasal sprays currently available as isotonic solutions, ciclesonide is in a hypotonic saline solution, which is somewhat more tolerable to patients, he said.
One of ciclesonide's advantages is that unlike most nasal sprays currently available as isotonic solutions, ciclesonide is in a hypotonic saline solution, which is somewhat more tolerable to patients, he said.
The use of isotonic solutions should eliminate the incidence of these potentially catastrophic complications.
The ability to effectively use isotonic solutions during hysteroscopic procedures would markedly reduce the risk of serious electrolyte disturbances and their associated complications and could well become the standard of care due to its higher margin of safety," noted Richard Gimpelson, M.